SCHEMBL10123717

SCHEMBL10123717

C(=C/c1ccc(N(c2ccc(-c3ccccc3)cc2)c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1)\c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.47
ATM Q13315 2/20 0.47
KDM4E B2RXH2 1/20 0.47
HDAC4 P56524 1/20 0.42
RELA Q04206 1/20 0.40
APP P05067 1/20 0.39
KMT2A Q03164 6/20 0.36
MEN1 O00255 5/20 0.36
MAPT P10636 4/20 0.36
ALDH1A1 P00352 2/20 0.36
USP2 O75604 2/20 0.36
AKR1C4 P17516 1/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
AKR1C1 Q04828 1/20 0.36
MAPK1 P28482 1/20 0.36
CTNNB1 P35222 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10123789 0.99 L3MBTL1 (0.49) L3MBTL1ATMKDM4EHDAC4RELA
SCHEMBL23616149 0.97 L3MBTL1 (0.47) L3MBTL1ATMKDM4EHDAC4RELA
SCHEMBL260506 0.93 KDM4E (0.52) L3MBTL1ATMKDM4EHDAC4RELA
SCHEMBL260507 0.93 KDM4E (0.52) L3MBTL1ATMKDM4EHDAC4RELA
SCHEMBL10123611 0.92 ATM (0.41) L3MBTL1ATMKDM4EHDAC4RELA
SCHEMBL36944 0.91 KDM4E (0.53) L3MBTL1ATMKDM4EHDAC4RELA
SCHEMBL275286 0.91 KDM4E (0.53) L3MBTL1ATMKDM4EHDAC4RELA
SCHEMBL36943 0.91 KDM4E (0.53) L3MBTL1ATMKDM4EHDAC4RELA
SCHEMBL276794 0.91 KDM4E (0.53) L3MBTL1ATMKDM4EHDAC4RELA
SCHEMBL29373027 0.91 KDM4E (0.53) L3MBTL1ATMKDM4EHDAC4RELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8901542-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-02 US disclosed
US-8901542-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-12-02 US disclosed
US-20120235130-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-20 US disclosed
US-20120235130-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-09-20 US disclosed
US-8193701-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-06-05 US disclosed
US-8193701-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-06-05 US disclosed
EP-1931634-B1 STILBENE DERIVATIVES, LIGHT-EMITTING ELEMENT AND LIGHT-EMITTING DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2011-11-09 EP disclosed
US-20110147729-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-20110147729-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-06-23 US disclosed
US-7898171-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-03-01 US disclosed
US-7898171-B2 Stilbene derivatives, light-emitting element and light-emitting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2011-03-01 US disclosed
US-20090146558-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2009-06-11 US disclosed
US-7476745-B2 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-13 US disclosed
US-7476745-B2 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-01-13 US disclosed
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-04-12 US disclosed
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090146558-A1 Stilbene Derivatives, Light-Emitting Element and Light-Emitting Device NR0B1, NR2E3, NR0B2 L3MBTL1 2135/4885ATM 1663/4885KDM4E 3101/4885
US-20070080630-A1 Such as 4-tert-butyl-4'-[N-(9-phenylcarbazol-3-yl)-N-phenylamino]stilbene; thinness, lightweight, and rapid response is expected to be applied to flat panel displays; excellent color purity of blue, luminous efficiency, durability NR0B1, TERB1, CYP1B1 L3MBTL1 1872/4885ATM 1342/4885KDM4E 1410/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.