SCHEMBL10124673

SCHEMBL10124673

CCON1C(C)(C)CC2(CC1(C)C)NC(=O)N(c1ccc(Cc3ccc(N4C(=O)NC5(CC(C)(C)N(OCC)C(C)(C)C5)C4=O)cc3)cc1)C2=O

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
TRIP13 Q15645 1/20 0.36
MGLL Q99685 2/20 0.36
FAAH O00519 1/20 0.36
AR P10275 5/20 0.34
MAPK1 P28482 1/20 0.33
ELANE P08246 2/20 0.33
ITGAL P20701 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
LMNA P02545 1/20 0.31
EGLN1 Q9GZT9 2/20 0.31
EGLN3 Q9H6Z9 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124648 0.87 ELANE (0.41) POLBNPC1RAB9AARELANE
SCHEMBL11479164 0.83 POLB (0.46) POLBNPC1RAB9ATRIP13MGLL
SCHEMBL10124653 0.78 ELANE (0.39) POLBNPC1RAB9AARELANE
SCHEMBL10124652 0.75 GAA (0.42) POLBNPC1RAB9AFAAHELANE
SCHEMBL10124655 0.75 GAA (0.42) POLBNPC1RAB9AFAAHELANE
SCHEMBL11478197 0.73 POLB (0.53) POLBNPC1RAB9AARMAPK1
SCHEMBL10124662 0.72 POLB (0.36) POLBNPC1RAB9AARALDH1A1
SCHEMBL10124651 0.72 POLB (0.42) POLBNPC1RAB9AARELANE
SCHEMBL10124670 0.71 CNR1 (0.39) ALDH1A1HTTSMN1; SMN2LMNA
SCHEMBL18697263 0.70 POLB (0.40) POLBNPC1RAB9AARELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440557-B1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2017-04-05 EP disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed
WO-2010142576-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2010-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS AAAS, CRY1, TAAR1 POLB 1620/4885NPC1 2178/4885RAB9A 3234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.