SCHEMBL10124653

SCHEMBL10124653

CCCON1C(C)(C)CC2(CC1(C)C)NC(=O)N(c1ccccc1)C2=O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ELANE P08246 5/20 0.39
POLB P06746 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
LMNA P02545 1/20 0.36
PGR P06401 1/20 0.35
MAPT P10636 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
EGLN1 Q9GZT9 2/20 0.35
EGLN3 Q9H6Z9 2/20 0.35
AR P10275 2/20 0.34
MEN1 O00255 1/20 0.34
GAA P10253 1/20 0.34
ALOX12 P18054 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124652 0.92 GAA (0.42) ELANEPOLBNPC1RAB9ALMNA
SCHEMBL10124655 0.92 GAA (0.42) ELANEPOLBNPC1RAB9ALMNA
SCHEMBL10124648 0.90 ELANE (0.41) ELANEPOLBNPC1RAB9ALMNA
SCHEMBL10124651 0.83 POLB (0.42) ELANEPOLBNPC1RAB9ALMNA
SCHEMBL10124662 0.82 POLB (0.36) POLBNPC1RAB9ALMNAMAPT
SCHEMBL18697263 0.81 POLB (0.40) ELANEPOLBNPC1RAB9ALMNA
SCHEMBL10124669 0.78 POLB (0.34) POLBNPC1RAB9AMAPTAR
SCHEMBL11483851 0.78 POLB (0.45) ELANEPOLBNPC1RAB9ALMNA
SCHEMBL10124680 0.78 ELANE (0.38) ELANEPGRMAPTNPSR1GAA
SCHEMBL10124673 0.78 POLB (0.41) ELANEPOLBNPC1RAB9ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS AAAS, CRY1, TAAR1 ELANE 2936/4885POLB 1620/4885NPC1 2178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.