SCHEMBL10124655

SCHEMBL10124655

CCCCCCCCCCCON1C(C)(C)CC2(CC1(C)C)NC(=O)N(c1ccccc1)C2=O

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.42
MEN1 O00255 1/20 0.42
ALOX12 P18054 1/20 0.42
KMT2A Q03164 1/20 0.42
ELANE P08246 4/20 0.40
ALDH1A1 P00352 4/20 0.36
MAPT P10636 4/20 0.36
SMN1; SMN2 Q16637 3/20 0.36
KDM4E B2RXH2 2/20 0.36
POLB P06746 1/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
FAAH O00519 1/20 0.36
PNKP Q96T60 1/20 0.35
LMNA P02545 2/20 0.34
HTT P42858 2/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124652 1.00 GAA (0.42) GAAMEN1ALOX12KMT2AELANE
SCHEMBL10124653 0.92 ELANE (0.39) GAAMEN1ALOX12KMT2AELANE
SCHEMBL10124648 0.87 ELANE (0.41) GAAELANEALDH1A1POLBNPC1
SCHEMBL10124682 0.81 ELANE (0.38) GAAMEN1ALOX12KMT2AELANE
SCHEMBL10124681 0.81 ELANE (0.38) GAAMEN1ALOX12KMT2AELANE
SCHEMBL10124651 0.80 POLB (0.42) ELANEALDH1A1POLBNPC1RAB9A
SCHEMBL18697263 0.78 POLB (0.40) ELANEALDH1A1POLBNPC1RAB9A
SCHEMBL10124667 0.78 ELANE (0.38) GAAMEN1ALOX12KMT2AELANE
SCHEMBL10124668 0.78 ELANE (0.38) GAAMEN1ALOX12KMT2AELANE
SCHEMBL10124697 0.77 GRM2 (0.35) GAAMEN1ALOX12KMT2AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS AAAS, CRY1, TAAR1 GAA 1442/4885MEN1 1632/4885ALOX12 2038/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.