SCHEMBL10124696

SCHEMBL10124696

CC1(C)CC2(CC(=O)N(c3ccccc3)C(=O)O2)CC(C)(C)N1OC1CCCCC1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MT-CO2 P00403 2/20 0.33
ALOX5 P09917 2/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
CYP3A4 P08684 1/20 0.32
RECQL P46063 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
ALDH1A1 P00352 3/20 0.32
CYP1A2 P05177 1/20 0.32
MAOA P21397 1/20 0.31
POLB P06746 1/20 0.31
TDP1 Q9NUW8 1/20 0.30
TNKS O95271 1/20 0.30
PTGS2 P35354 1/20 0.30
HSD11B1 P28845 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124678 0.83 CACNA1B (0.35) MT-CO2ALOX5CACNA1BAPBA1CYP2C9
SCHEMBL10124693 0.83 ALDH1A1 (0.39) CACNA1BAPBA1CYP2C9CYP2C19CYP3A4
SCHEMBL13050168 0.82 ALDH1A1 (0.35) CACNA1BAPBA1CYP2C9CYP2C19ALDH1A1
SCHEMBL18697204 0.81 ALDH1A1 (0.35) CACNA1BAPBA1CYP2C9CYP2C19CYP3A4
SCHEMBL10124692 0.80 ALDH1A1 (0.36) CACNA1BAPBA1CYP2C9CYP2C19ALDH1A1
SCHEMBL10124699 0.78 POLB (0.31) POLB
SCHEMBL10124695 0.78 ELANE (0.33) CACNA1BAPBA1CYP2C9CYP2C19NPSR1
SCHEMBL10124654 0.75 POLB (0.42) MT-CO2ALOX5CACNA1BAPBA1ALDH1A1
SCHEMBL10151302 0.75
SCHEMBL10124697 0.74 GRM2 (0.35) CYP2C9CYP2C19RECQLNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440557-B1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2017-04-05 EP disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed
WO-2010142576-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2010-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS AAAS, CRY1, TAAR1 MT-CO2 3662/4885ALOX5 1740/4885CACNA1B 4469/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.