SCHEMBL10124692

SCHEMBL10124692

CCON1C(C)(C)CC2(CC(=O)N(c3ccccc3)C(=O)O2)CC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
GAA P10253 2/20 0.36
ELANE P08246 4/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
MAPK1 P28482 1/20 0.34
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
CACNA1B Q00975 1/20 0.33
APBA1 Q02410 1/20 0.33
HSD11B1 P28845 1/20 0.32
SLC6A2 P23975 1/20 0.32
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
CASP1 P29466 1/20 0.31
CASP3 P42574 1/20 0.31
CASP7 P55210 1/20 0.31
SENP8 Q96LD8 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10124695 0.91 ELANE (0.33) ALDH1A1GAAELANECYP1A2CYP2C9
SCHEMBL10124698 0.87 GRM2 (0.35) ALDH1A1GAAELANECYP2C9CYP2C19
SCHEMBL10124697 0.87 GRM2 (0.35) ALDH1A1GAAELANECYP2C9CYP2C19
SCHEMBL10124693 0.86 ALDH1A1 (0.39) ALDH1A1GAAELANECYP1A2CYP2C9
SCHEMBL13050168 0.85 ALDH1A1 (0.35) ALDH1A1GAAELANECYP1A2CYP2C9
SCHEMBL18697204 0.84 ALDH1A1 (0.35) ALDH1A1GAAELANECYP1A2CYP2C9
SCHEMBL10124677 0.81 ELANE (0.39) ALDH1A1GAAELANECACNA1BAPBA1
SCHEMBL10124704 0.80 TRIP13 (0.33) ALDH1A1MAPK1CACNA1BAPBA1
SCHEMBL10124696 0.80 MT-CO2 (0.33) ALDH1A1CYP1A2CYP2C9CYP2C19CACNA1B
SCHEMBL18697229 0.79 KMT2A (0.34) ELANEMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2440557-B1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2017-04-05 EP disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-9045480-B2 Sterically hindered amine light stabilizers BASF SE (DE) 2015-06-02 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2012-05-03 US disclosed
WO-2010142576-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS BASF SE (DE) 2010-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120108709-A1 NOVEL STERICALLY HINDERED AMINE LIGHT STABILIZERS AAAS, CRY1, TAAR1 ALDH1A1 390/4885GAA 1442/4885ELANE 2936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.