Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.31 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12346596 | 0.83 | L3MBTL1 (0.43) | L3MBTL1BRD4ACVR1PKMCYP2C19 | |
| SCHEMBL12346678 | 0.83 | L3MBTL1 (0.44) | L3MBTL1BRD4PKMPIK3C3POLB | |
| SCHEMBL14494739 | 0.82 | L3MBTL1 (0.43) | L3MBTL1BRD4PKMCYP2C19RAPGEF4 | |
| SCHEMBL12346617 | 0.82 | L3MBTL1 (0.40) | L3MBTL1BRD4CYP2C19PIK3C3MEN1 | |
| SCHEMBL10125007 | 0.81 | L3MBTL1 (0.44) | L3MBTL1BRD4ACVR1PKMPIK3C3 | |
| SCHEMBL16380561 | 0.80 | L3MBTL1 (0.40) | L3MBTL1BRD4PIK3C3POLBMEN1 | |
| SCHEMBL10125001 | 0.80 | L3MBTL1 (0.49) | L3MBTL1BRD4PKMCYP2C19RAPGEF4 | |
| SCHEMBL2237896 | 0.78 | L3MBTL1 (0.62) | L3MBTL1BRD4PKMCYP2C19RAPGEF4 | |
| SCHEMBL8240504 | 0.77 | L3MBTL1 (0.46) | L3MBTL1BRD4PKMCYP2C19RAPGEF4 | |
| SCHEMBL1779961 | 0.72 | L3MBTL1 (0.57) | L3MBTL1BRD4PKMCYP2C19RAPGEF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881983-B1 | PYRROLOPYRIDINES USEFUL AS INHIBITORS OF PROTEIN KINASE | VERTEX PHARMA (US) | 2012-01-11 | — | — | EP | disclosed |