⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30656266 | 0.83 | LMNA (0.34) | — | |
| SCHEMBL2330633 | 0.67 | — | — | |
| SCHEMBL737601 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL6392648 | 0.64 | — | — | |
| SCHEMBL276906 | 0.62 | — | — | |
| SCHEMBL7364624 | 0.60 | — | — | |
| Pyridine SCHEMBL10972834 | 0.57 | NAPRT (0.60) | — | |
| SCHEMBL22322736 | 0.56 | — | — | |
| SCHEMBL219949 | 0.54 | PKM (0.33) | — | |
| Pyridazine SCHEMBL663154 | 0.54 | LMNA (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195489-A | Novel alkoxyaminopyridine derivatives for the treatment of pain and pain-related disorders | 埃斯特韦制药股份公司 | 2021-07-30 | — | — | CN | claimed |
| CN-113166147-A | Novel tetrahydropyrimidine diazepine and tetrahydropyridine diazepine compounds for the treatment of pain and pain-related disorders | 埃斯特韦制药股份公司 | 2021-07-23 | — | — | CN | claimed |
| CN-111566091-A | Novel alkoxyamino derivatives for the treatment of pain and pain related disorders | 埃斯特韦制药有限公司 | 2020-08-21 | — | — | CN | claimed |
| CN-111298127-A | Composition comprising histamine release-promoting substance and inhibitory compound, and oral solid preparation containing the same | 黄泳华 | 2020-06-19 | — | — | CN | claimed |
| EP-2665724-A1 | BICYCLIC INHIBITORS OF ALK | AbbVie Inc. (US) | 2013-11-27 | — | — | EP | claimed |
| WO-2012097682-A1 | BICYCLIC INHIBITORS OF ALK | ABBOTT LABORATORIES (US) | 2012-07-26 | — | — | WO | claimed |
| EP-1784390-A2 | SUBSTITUTED BENZOFUSED HETEROCYCLES | Amgen Inc. (US) | 2007-05-16 | — | — | EP | claimed |
| EP-1227103-B1 | Ring-expanded nucleosides and nucleotides | NABI (US) | 2006-07-26 | — | — | EP | claimed |
| WO-2006020959-A2 | SUBSTITUTED BENZOFUSED HETEROCYCLES | AMGEN INC. (US) | 2006-02-23 | — | — | WO | claimed |
| EP-0724587-B8 | RING-EXPANDED NUCLEOSIDES AND NUCLEOTIDES | NABI (US) | 2003-01-29 | — | — | EP | claimed |
| EP-1227103-A2 | Ring-expanded nucleosides and nucleotides | Nabi (US) | 2002-07-31 | — | — | EP | claimed |
| US-5843912-A | Ring-expanded nucleosides and nucleotides | UNIVERSY OF MARYLAND (US) | 1998-12-01 | — | — | US | claimed |
| EP-0724587-A4 | RING-EXPANDED NUCLEOSIDES AND NUCLEOTIDES | BURNS BARRY (US) | 1996-12-27 | — | — | EP | claimed |
| EP-0724587-A1 | RING-EXPANDED NUCLEOSIDES AND NUCLEOTIDES | Burns, Barry (US) | 1996-08-07 | — | — | EP | claimed |
| WO-1995009175-A1 | RING-EXPANDED NUCLEOSIDES AND NUCLEOTIDES | BURNS BARRY (US) | 1995-04-06 | — | — | WO | claimed |
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |
| CN-118215676-A | Specific conjugation of antibody drug conjugates | 杭州多禧生物科技有限公司 | 2024-06-18 | — | — | CN | disclosed |
| EP-0724587-A1 | RING-EXPANDED NUCLEOSIDES AND NUCLEOTIDES | Burns, Barry (US) | 1996-08-07 | — | — | EP | disclosed |
| WO-1995009175-A1 | RING-EXPANDED NUCLEOSIDES AND NUCLEOTIDES | BURNS BARRY (US) | 1995-04-06 | — | — | WO | disclosed |
| WO-1981000568-A1 | BENZODIAZEPINONES,A PROCESS FOR THEIR PREPARATION,THEIR USE AND MEDICAMENTS CONTAINING THEM | BYK GULDEN LOMBERG CHEM FAB (DE) | 1981-03-05 | — | — | WO | disclosed |