Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 12/20 | 0.65 |
| ▸ | RAB9A | P51151 | 12/20 | 0.65 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
| ▸ | MMP13 | P45452 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | HPGD | P15428 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10125852 | 0.97 | NPC1 (0.62) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL10315409 | 0.89 | NPC1 (0.55) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL10126033 | 0.89 | KDM4E (0.73) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL10125924 | 0.88 | TDP1 (0.60) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL19601392 | 0.88 | NPC1 (0.72) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL10315173 | 0.88 | NPC1 (0.54) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL12408905 | 0.86 | NPC1 (0.84) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL10125853 | 0.86 | KDM4E (0.78) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL436386 | 0.85 | NPC1 (0.76) | NPC1RAB9AMMP2MMP9MMP8 | |
| SCHEMBL11551873 | 0.85 | NPC1 (0.81) | NPC1RAB9AMMP2MMP9MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119259-B2 | Quinoxaline derivative, and light-emitting element and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-8119259-B2 | Quinoxaline derivative, and light-emitting element and electronic device using the same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2012-02-21 | — | — | US | disclosed |
| US-20090140642-A1 | Quinoxaline Derivative, and Light-Emitting Element and Electronic Device Using the Same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-06-04 | — | — | US | disclosed |
| US-20090140642-A1 | Quinoxaline Derivative, and Light-Emitting Element and Electronic Device Using the Same | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2009-06-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090140642-A1 | Quinoxaline Derivative, and Light-Emitting Element and Electronic Device Using the Same | NDUFA11, NDUFA9, NDUFA12 | NPC1 4763/4885RAB9A 1141/4885MMP2 4721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.