SCHEMBL10126692

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10127142	0.85	PDE4B (0.45)	PPARGPDE4BCA1CA2CA7
	SCHEMBL17069444	0.82	LMNA (0.47)	PPARGMAPTRXFP1LMNA
	SCHEMBL10127040	0.82	TP53 (0.46)	PPARGTP53
	SCHEMBL10127090	0.81	CA1 (0.48)	PPARGPDE4BCA1CA2CA7
	SCHEMBL283538	0.81	RAB9A (0.46)	PPARGMAPTPOLBLMNAKDM4E
	SCHEMBL10127045	0.81	MAPT (0.45)	PPARGCA1CA2CA7MAPT
	SCHEMBL10127156	0.80	PPARG (0.43)	PPARGPDE4BMAPTPOLBRXFP1
	SCHEMBL10127219	0.80	MAPKAPK2 (0.45)	PPARGCA1CA2CA7CA13
	SCHEMBL10127227	0.80	CA1 (0.40)	PPARGCA1CA2CA7CA13
	SCHEMBL10127210	0.79	GSK3B (0.44)	PPARGMAPTGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.