Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | CES1 | P23141 | 4/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.38 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.38 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.38 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.38 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.38 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.38 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.38 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.38 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.38 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.38 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.38 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1012685 | 1.00 | CES2 (0.48) | CES2CES1CA3CA6CA5A | |
| SCHEMBL12909551 | 0.86 | CES2 (0.50) | CES2CES1CA3CA6CA5A | |
| SCHEMBL9521302 | 0.85 | CES2 (0.48) | CES2CES1ALDH1A1 | |
| SCHEMBL7475182 | 0.85 | CES2 (0.48) | CES2CES1ALDH1A1 | |
| SCHEMBL7481905 | 0.85 | CES2 (0.48) | CES2CES1ALDH1A1 | |
| SCHEMBL28077039 | 0.79 | CES2 (0.43) | CES2CES1CA3CA6CA5A | |
| SCHEMBL21990664 | 0.77 | CES2 (0.64) | CES2CES1CA3CA6CA5A | |
| SCHEMBL30485128 | 0.77 | CES2 (0.64) | CES2CES1CA3CA6CA5A | |
| SCHEMBL13580704 | 0.77 | CES2 (0.64) | CES2CES1CA3CA6CA5A | |
| SCHEMBL2563657 | 0.77 | CES2 (0.64) | CES2CES1CA3CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076494-B2 | Process for the manufacture of epoxy triazole derivatives | BASILEA PHARMACEUTICA AG (CH) | 2011-12-13 | — | — | US | disclosed |
| US-20110021794-A1 | Process for the manufacture of epoxy triazole derivatives | MULLER MARC | 2011-01-27 | — | — | US | disclosed |
| US-7816537-B2 | Process for the manufacture of epoxybutanol intermediates | BASILEA PHARMACEUTICA AG (CH) | 2010-10-19 | — | — | US | disclosed |
| EP-2133345-A1 | PROCESS FOR THE MANUFACTURE OF EPOXYBUTANOL INTERMEDIATES | Basilea Pharmaceutica AG (CH) | 2009-12-16 | — | — | EP | disclosed |
| US-20090299073-A1 | Process for the Manufacture of Epoxybutanol Intermediates | MULLER MARC | 2009-12-03 | — | — | US | disclosed |
| EP-1954264-B1 | PROCESS FOR THE MANUFACTURE OF EPOXYBUTANOL INTERMEDIATES | BASILEA PHARMACEUTICA AG (CH) | 2009-10-07 | — | — | EP | disclosed |
| EP-1954264-A2 | PROCESS FOR THE MANUFACTURE OF EPOXYBUTANOL INTERMEDIATES | Basilea Pharmaceutica AG (CH) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007062542-A2 | PROCESS FOR THE MANUFACTURE OF EPOXYBUTANOL INTERMEDIATES | BASILEA PHARMACEUTICA AG (CH) | 2007-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110021794-A1 | Process for the manufacture of epoxy triazole derivatives | POR, CYP2E1, CYP1A1 | CES2 70/4885CES1 159/4885CA3 845/4885 |
| US-20090299073-A1 | Process for the Manufacture of Epoxybutanol Intermediates | POR, CYP4A11, CYP1A1 | CES2 58/4885CES1 158/4885CA3 1680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.