SCHEMBL21990664

SCHEMBL21990664

CC(O)C(=O)c1cc(F)ccc1F

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.64
CES1 P23141 4/20 0.64
MDM2 Q00987 10/20 0.47
PSMB11 A5LHX3 1/20 0.44
PSMA7 O14818 1/20 0.44
PSMB1 P20618 1/20 0.44
PSMA1 P25786 1/20 0.44
PSMA2 P25787 1/20 0.44
PSMA3 P25788 1/20 0.44
PSMA4 P25789 1/20 0.44
PSMB8 P28062 1/20 0.44
PSMB9 P28065 1/20 0.44
PSMA5 P28066 1/20 0.44
PSMB4 P28070 1/20 0.44
PSMB6 P28072 1/20 0.44
PSMB5 P28074 1/20 0.44
PSMB10 P40306 1/20 0.44
PSMB3 P49720 1/20 0.44
PSMB2 P49721 1/20 0.44
PSMA6 P60900 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13580704 1.00 CES2 (0.64) CES2CES1MDM2PSMB11PSMA7
SCHEMBL30485128 1.00 CES2 (0.64) CES2CES1MDM2PSMB11PSMA7
SCHEMBL2563657 1.00 CES2 (0.64) CES2CES1MDM2PSMB11PSMA7
SCHEMBL12909549 0.86 CES2 (0.61) CES2CES1MDM2PSMB11PSMA7
SCHEMBL30485086 0.85 CES2 (0.64) CES2CES1PSMB5
SCHEMBL2562024 0.85 CES2 (0.64) CES2CES1PSMB5
SCHEMBL940243 0.85 CES2 (0.64) CES2CES1PSMB5
SCHEMBL9046982 0.85 CES2 (0.64) CES2CES1PSMB5
SCHEMBL5744377 0.83 CES2 (0.57) CES2CES1MDM2PSMB11PSMA7
SCHEMBL23571753 0.80 CES2 (0.54) CES2CES1MDM2PSMB11PSMA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110997646-B Process for producing epoxy alcohol compound 住友化学株式会社 2023-06-20 CN disclosed
EP-3666762-B1 METHOD FOR PRODUCING EPOXY ALCOHOL COMPOUND SUMITOMO CHEMICAL CO (JP) 2022-04-06 EP disclosed
US-10730861-B2 Process for producing epoxy alcohol compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-08-04 US disclosed
EP-3666762-A1 METHOD FOR PRODUCING EPOXY ALCOHOL COMPOUND Sumitomo Chemical Company, Limited (JP) 2020-06-17 EP disclosed
US-20200172520-A1 PROCESS FOR PRODUCING EPOXY ALCOHOL COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2020-06-04 US disclosed
CN-110997646-A Method for producing epoxy alcohol compound 住友化学株式会社 2020-04-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200172520-A1 PROCESS FOR PRODUCING EPOXY ALCOHOL COMPOUND ERG28, CYP2E1, ADH5 CES2 1409/4885CES1 776/4885MDM2 4842/4885
US-10730861-B2 Process for producing epoxy alcohol compound ERG28, CYP2E1, ADH5 CES2 1409/4885CES1 776/4885MDM2 4842/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.