SCHEMBL10127174

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17689744	0.90	RXFP1 (0.41)	PPARGRXFP1NCOR2XDHNTRK1
	SCHEMBL17340298	0.85	RXFP1 (0.39)	PPARGRXFP1NCOR2XDHNTRK1
	SCHEMBL10127183	0.84	RXFP1 (0.41)	RXFP1XDHPOLBALDH1A1KDM4E
	SCHEMBL10127216	0.81	GSK3A (0.39)	PPARGRXFP1NCOR2XDHPDE4B
	SCHEMBL10126689	0.81	PDE4B (0.45)	PPARGRXFP1NCOR2XDHPOLB
	SCHEMBL10127156	0.78	PPARG (0.43)	PPARGRXFP1POLBNTRK1ALDH1A1
	SCHEMBL10127150	0.78	XDH (0.46)	PPARGRXFP1NCOR2XDHKDM4E
	SCHEMBL283685	0.76	ALK (0.40)	NTRK1
	SCHEMBL10127260	0.75	PNP (0.41)	RXFP1XDHNTRK1PDE4B
	SCHEMBL10127167	0.75	NTRK1 (0.38)	PPARGRXFP1POLBNTRK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.