Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 4/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10127174 | 0.90 | PPARG (0.42) | RXFP1PPARGNCOR2XDHNTRK1 | |
| SCHEMBL17340298 | 0.88 | RXFP1 (0.39) | RXFP1PPARGNCOR2XDHNTRK1 | |
| SCHEMBL10127183 | 0.74 | RXFP1 (0.41) | RXFP1XDHALDH1A1KDM4ELMNA | |
| SCHEMBL10127216 | 0.71 | GSK3A (0.39) | RXFP1PPARGNCOR2XDH | |
| SCHEMBL10127156 | 0.71 | PPARG (0.43) | RXFP1PPARGNTRK1ALDH1A1HPGD | |
| SCHEMBL10126689 | 0.70 | PDE4B (0.45) | RXFP1PPARGNCOR2XDHALDH1A1 | |
| SCHEMBL10127150 | 0.68 | XDH (0.46) | RXFP1PPARGNCOR2XDHKDM4E | |
| SCHEMBL10127167 | 0.68 | NTRK1 (0.38) | RXFP1PPARGNTRK1ALDH1A1TP53 | |
| SCHEMBL328281 | 0.67 | XDH (0.38) | RXFP1XDHALDH1A1KDM4ELMNA | |
| SCHEMBL283685 | 0.66 | ALK (0.40) | NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2428508-B9 | DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND | ASTELLAS PHARMA INC (JP) | 2016-04-20 | — | — | EP | disclosed |