SCHEMBL10128875

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19473644	1.00	CYP2A6 (0.35)	CYP2A6CYP1A2HTTNPSR1L3MBTL1
	SCHEMBL13040200	0.94	AKR1B1 (0.37)	CYP2A6CYP1A2CNR2AKR1B1CNR1
	SCHEMBL29360067	0.89	CYP1A2 (0.42)	CYP2A6CYP1A2HTTNPSR1L3MBTL1
	SCHEMBL36539	0.89	CYP1A2 (0.42)	CYP2A6CYP1A2HTTNPSR1L3MBTL1
	SCHEMBL12292428	0.88	UGT2B7 (0.41)	CYP1A2KDM1AUGT2B7KIF11GAA
	SCHEMBL12292392	0.88	CNR2 (0.39)	CNR2CNR1KDM1AKIF11GAA
	SCHEMBL3284757	0.84	CYP1A2 (0.44)	CYP2A6CYP1A2HTTNPSR1L3MBTL1
	SCHEMBL13070429	0.84	CYP2A6 (0.34)	CYP2A6CYP1A2HTTNPSR1L3MBTL1
	SCHEMBL29512016	0.83	CNR2 (0.37)	CNR2CNR1KDM1AKIF11GAA
	SCHEMBL10132148	0.83	CNR2 (0.37)	CNR2CNR1KDM1AKIF11GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.