SCHEMBL10132148

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29512016	1.00	CNR2 (0.37)	CNR2CNR1SRCKIF11CHRNA7
	SCHEMBL12292392	0.95	CNR2 (0.39)	CNR2CNR1SRCKIF11CHRNA7
	SCHEMBL13010106	0.90	CNR2 (0.38)	CNR2CNR1SRCKIF11CHRNA7
	SCHEMBL12292391	0.89	KIF11 (0.33)	KIF11CYP2C19DHODHALDH1A1MAPT
	SCHEMBL2540242	0.88	ALDH1A1 (0.39)	CYP2C19ALDH1A1TSHRMAPTACHE
	SCHEMBL12292394	0.88	KIF11 (0.39)	CNR2CNR1KIF11CYP2C19DHODH
	SCHEMBL16066045	0.86	CNR1 (0.34)	CNR2CNR1KIF11CHRNA7
	SCHEMBL12292407	0.86	KIF11 (0.33)	CNR2KIF11TSHR
	SCHEMBL12292412	0.85	ACHE (0.39)	CNR2CNR1KIF11DHODHTP53
	SCHEMBL24012585	0.85	TSHR (0.43)	CNR2CNR1ALDH1A1TSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.