SCHEMBL10128923

SCHEMBL10128923

C(=C/c1ccc(N(c2ccccc2)c2ccc(-c3ccccc3)c3ccccc23)cc1)\c1ccc(N(c2ccccc2)c2ccc(-c3ccccc3)c3ccccc23)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
ALDH1A1 P00352 4/20 0.45
L3MBTL1 Q9Y468 4/20 0.45
MAPK1 P28482 3/20 0.45
MAPT P10636 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
USP2 O75604 1/20 0.45
CTNNB1 P35222 1/20 0.45
ATM Q13315 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
APP P05067 1/20 0.42
RELA Q04206 1/20 0.41
RXRA P19793 1/20 0.38
RXRB P28702 1/20 0.38
PELI1 Q96FA3 1/20 0.33
CTDSP1 Q9GZU7 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
NPC1 O15118 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13021479 0.95 APP (0.44) MEN1KMT2AALDH1A1L3MBTL1MAPK1
SCHEMBL12442796 0.95 APP (0.44) MEN1KMT2AALDH1A1L3MBTL1MAPK1
SCHEMBL12128636 0.95 RXRA (0.42) MEN1KMT2AALDH1A1L3MBTL1MAPK1
SCHEMBL9971858 0.94 APP (0.43) MEN1KMT2AALDH1A1L3MBTL1MAPK1
SCHEMBL10128937 0.90 RELA (0.47) MEN1KMT2AALDH1A1L3MBTL1MAPK1
SCHEMBL13380714 0.89 ALDH1A1 (0.44) MEN1KMT2AALDH1A1L3MBTL1MAPK1
SCHEMBL9971782 0.88 RELA (0.48) MEN1KMT2AALDH1A1L3MBTL1MAPK1
SCHEMBL3433784 0.88 RELA (0.52) MEN1KMT2AALDH1A1L3MBTL1MAPK1
SCHEMBL9971905 0.88 RELA (0.52) MEN1KMT2AALDH1A1L3MBTL1MAPK1
SCHEMBL24106777 0.88 RXRA (0.45) MEN1KMT2AALDH1A1L3MBTL1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8207526-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-06-26 US disclosed
US-8207526-B2 Organic EL device IDEMITSU KOSAN CO., LTD. (JP) 2012-06-26 US disclosed
US-20100259163-A1 POLYMER COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-10-14 US disclosed
US-20100259163-A1 POLYMER COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2010-10-14 US disclosed
US-20100044689-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-02-25 US disclosed
US-20100044689-A1 ORGANIC EL DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2010-02-25 US disclosed