Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30262599 | 1.00 | IDO1 (0.43) | IDO1RXFP1KCNJ11HDAC1HDAC6 | |
| SCHEMBL21807214 | 0.85 | RXFP1 (0.42) | IDO1RXFP1KCNJ11HDAC1HDAC6 | |
| SCHEMBL1494522 | 0.83 | KMT2A (0.37) | IDO1HDAC1HDAC6CA1CA2 | |
| SCHEMBL29181923 | 0.81 | RXFP1 (0.39) | IDO1RXFP1KCNJ11HDAC1HDAC6 | |
| SCHEMBL30387764 | 0.81 | L3MBTL1 (0.44) | CA1CA2CA9SMN1; SMN2ALDH1A1 | |
| SCHEMBL28439006 | 0.81 | L3MBTL1 (0.44) | CA1CA2CA9SMN1; SMN2ALDH1A1 | |
| SCHEMBL25383118 | 0.80 | RXFP1 (0.38) | IDO1RXFP1KCNJ11HDAC1HDAC6 | |
| SCHEMBL30574916 | 0.80 | RXFP1 (0.38) | IDO1RXFP1KCNJ11HDAC1HDAC6 | |
| SCHEMBL30956710 | 0.79 | ALDH1A1 (0.44) | HDAC1HDAC6CA1CA2CA9 | |
| SCHEMBL20833608 | 0.79 | ALDH1A1 (0.44) | HDAC1HDAC6CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617273-A1 | FUSED TRICYCLIC PARP1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | Haihe Biopharma Co., Ltd. (CN) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024099416-A1 | FUSED TRICYCLIC PARP1 INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2024-05-16 | — | — | WO | disclosed |
| CN-118005637-A | Fused tricyclic PARP1 inhibitor, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-110545811-B | Remote heteroarene alkylation using a catalytic bifunctional template | 斯克利普斯研究院 | 2023-02-14 | — | — | CN | disclosed |
| US-10858383-B2 | Remote heteroaryl alkenylation with catalytic bifunctional template | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-12-08 | — | — | US | disclosed |
| US-20200131213-A1 | Remote Heteroaryl Alkenylation With Catalytic Bifunctional Template | THE SCRIPPS RESEARCH INSTITUTE | 2020-04-30 | — | — | US | disclosed |
| CN-110545811-A | remote heteroarene alkylation using a catalytic bifunctional template | SCRIPPS RES INSTITUTE | 2019-12-06 | — | — | CN | disclosed |
| WO-2018152107-A1 | REMOTE HETEROARYL ALKENYLATION WITH CATALYTIC BIFUNCTIONAL TEMPLATE | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-08-23 | — | — | WO | disclosed |
| EP-2655355-B1 | NEW TRIAZOLYLPHENYL SULFONAMIDES AS SERINE/THREONINE KINASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2015-03-18 | — | — | EP | disclosed |
| US-8710055-B2 | Triazolylphenyl sulfonamides as serine/threonine kinase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-04-29 | — | — | US | disclosed |
| US-20120322803-A1 | Triazolylphenyl sulfonamides as serine/threonine kinase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-12-20 | — | — | US | disclosed |
| WO-2012085127-A1 | NEW TRIAZOLYLPHENYL SULFONAMIDES AS SERINE/THREONINE KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322803-A1 | Triazolylphenyl sulfonamides as serine/threonine kinase inhibitors | CDK2, TNNI3K, CDK1 | IDO1 2823/4885RXFP1 3154/4885KCNJ11 2385/4885 |
| US-20200131213-A1 | Remote Heteroaryl Alkenylation With Catalytic Bifunctional Template | APEH, ALKBH3, JMJD7 | IDO1 594/4885RXFP1 4808/4885KCNJ11 2193/4885 |
| US-10858383-B2 | Remote heteroaryl alkenylation with catalytic bifunctional template | APEH, ALKBH3, JMJD7 | IDO1 594/4885RXFP1 4808/4885KCNJ11 2193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.