SCHEMBL10130405

SCHEMBL10130405

c1ccc(-c2cccc(-c3c4ccccc4c(-c4cccc(-c5ccccc5)c4)c4cc(-c5cccc(-c6cc7ccccc7c7c6oc6ccccc67)c5)ccc34)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.39
PLA2G4A P47712 3/20 0.39
PLA2G10 O15496 1/20 0.39
ALOX5 P09917 1/20 0.38
GPR84 Q9NQS5 4/20 0.37
TDP1 Q9NUW8 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PIM1 P11309 1/20 0.34
CSNK2A2 P19784 1/20 0.34
CSNK2B P67870 1/20 0.34
PIM3 Q86V86 1/20 0.34
PIM2 Q9P1W9 1/20 0.34
KDM4E B2RXH2 2/20 0.34
RAB9A P51151 2/20 0.34
ALDH1A1 P00352 1/20 0.34
MAOB P27338 1/20 0.34
HSD17B1 P14061 1/20 0.34
HSD17B2 P37059 1/20 0.34
CDC14B O60729 1/20 0.34
CDC14A Q9UNH5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18996163 0.99 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10ALOX5GPR84
SCHEMBL10130456 0.99 PLA2G2A (0.38) PLA2G2APLA2G4APLA2G10ALOX5GPR84
SCHEMBL10130395 0.98 PLA2G2A (0.39) PLA2G2APLA2G4APLA2G10ALOX5GPR84
SCHEMBL10130442 0.96 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10ALOX5GPR84
SCHEMBL9949773 0.96 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10ALOX5GPR84
SCHEMBL29406326 0.96 PLA2G2A (0.40) PLA2G2APLA2G4APLA2G10ALOX5GPR84
SCHEMBL10130410 0.94 GPR84 (0.41) PLA2G2APLA2G4APLA2G10ALOX5GPR84
SCHEMBL10130465 0.94 ALOX5 (0.40) PLA2G2APLA2G4APLA2G10ALOX5GPR84
SCHEMBL9951354 0.93 GPR84 (0.41) PLA2G2APLA2G4APLA2G10ALOX5GPR84
SCHEMBL10130437 0.93 GPR84 (0.41) PLA2G2APLA2G4APLA2G10ALOX5GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material CYP1B1, CTNND1, CTNNB1 PLA2G2A 1889/4885PLA2G4A 2242/4885PLA2G10 2897/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.