SCHEMBL10130417

SCHEMBL10130417

c1ccc(C2(c3ccccc3)c3ccccc3-c3ccc(-c4c5ccccc5c(-c5ccc6c(c5)C(c5ccccc5)(c5ccccc5)c5ccccc5-6)c5cc(-c6cccc(-c7cc8ccccc8c8c7oc7ccccc78)c6)ccc45)cc32)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.33
PLA2G10 O15496 1/20 0.32
PLA2G2A P14555 1/20 0.32
PLA2G4A P47712 1/20 0.32
CDC14B O60729 1/20 0.30
CDC14A Q9UNH5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10130419 0.96 ALOX5 (0.34) ALOX5PLA2G10PLA2G2APLA2G4ACDC14B
SCHEMBL10130415 0.89 ALOX5 (0.33) ALOX5PLA2G10PLA2G2APLA2G4ACDC14B
SCHEMBL12539409 0.87 ALOX5 (0.44) ALOX5PLA2G10PLA2G2APLA2G4A
SCHEMBL10130405 0.86 PLA2G2A (0.39) ALOX5PLA2G10PLA2G2APLA2G4ACDC14B
SCHEMBL18996163 0.85 PLA2G2A (0.38) ALOX5PLA2G10PLA2G2APLA2G4ACDC14B
SCHEMBL10130456 0.85 PLA2G2A (0.38) ALOX5PLA2G10PLA2G2APLA2G4ACDC14B
SCHEMBL29406326 0.85 PLA2G2A (0.40) ALOX5PLA2G10PLA2G2APLA2G4ACDC14B
SCHEMBL10130442 0.85 PLA2G2A (0.40) ALOX5PLA2G10PLA2G2APLA2G4ACDC14B
SCHEMBL9949773 0.85 PLA2G2A (0.40) ALOX5PLA2G10PLA2G2APLA2G4ACDC14B
SCHEMBL10130395 0.84 PLA2G2A (0.39) ALOX5PLA2G10PLA2G2APLA2G4ACDC14B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120165556-A1 Benzo[b]Naphtho[1,2-d]Furan Compound as Light-Emitting Element Material CYP1B1, CTNND1, CTNNB1 ALOX5 1628/4885PLA2G10 2897/4885PLA2G2A 1889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.