SCHEMBL1013083

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1043394	0.85	KIF11 (0.50)	KMT2AKDM4EALDH1A1CSNK1DMAPK11
	SCHEMBL31146997	0.84	SMARCA2 (0.46)	KMT2ACSNK1DMAPK11MAPK14MEN1
	SCHEMBL1013453	0.82	AKT1 (0.42)	KMT2AKDM4EALDH1A1CSNK1DMAPK11
	SCHEMBL1598971	0.78	MAPK14 (0.60)	ALDH1A1CSNK1DMAPK11MAPK14NPC1
	SCHEMBL1042340	0.73	SRC (0.45)	KDM4EALDH1A1MAPK14KIF11
	SCHEMBL29206155	0.72	EGFR (0.54)	KMT2AALDH1A1MEN1NPC1NR2F2
	SCHEMBL4904785	0.72	KIF11 (0.48)	KMT2AALDH1A1MEN1NPC1NR2F2
	SCHEMBL28033855	0.72	PLK4 (0.41)	KMT2AKDM4EALDH1A1MEN1AKT1
	SCHEMBL1041869	0.71	PTPN1 (0.42)	KDM4EALDH1A1HSD17B2KIF11
	SCHEMBL1040395	0.71	CSNK1D (0.48)	KDM4EALDH1A1CSNK1DMAPK11MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.