SCHEMBL10130847

SCHEMBL10130847

CCc1cc(CO)c(O)c(OC)c1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.52
TRPV1 Q8NER1 1/20 0.49
TNKS2 Q9H2K2 1/20 0.46
PDE4A P27815 1/20 0.46
PDE4B Q07343 1/20 0.46
PDE4C Q08493 1/20 0.46
PDE4D Q08499 1/20 0.46
ALOX5 P09917 5/20 0.44
SHBG P04278 1/20 0.43
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
AKR1B1 P15121 1/20 0.41
GAA P10253 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 1/20 0.40
CASP6 P55212 1/20 0.40
MAPT P10636 2/20 0.40
HSPA5 P11021 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL829369 0.89 KDM4E (0.52) PTGS2TRPV1TNKS2PDE4APDE4B
SCHEMBL211114 0.87 SHBG (0.58) TRPV1TNKS2PDE4APDE4BPDE4C
SCHEMBL930805 0.87 TNKS2 (0.56) PTGS2TRPV1TNKS2PDE4APDE4B
SCHEMBL19004135 0.87 PTGS2 (0.53) PTGS2TRPV1TNKS2ALOX5NFKB1
SCHEMBL15221748 0.86 TNKS2 (0.51) PTGS2TRPV1TNKS2PDE4APDE4B
SCHEMBL14606346 0.85 SHBG (0.56) TRPV1TNKS2PDE4APDE4BPDE4C
SCHEMBL10130966 0.85 TRPV1 (0.52) PTGS2TRPV1TNKS2PDE4APDE4B
SCHEMBL901445 0.84 PTGS2 (0.64) PTGS2TNKS2ALOX5AKR1B1GAA
SCHEMBL15394651 0.83 TNKS2 (0.57) PTGS2TRPV1TNKS2ALOX5NFKB1
Methane SCHEMBL29229953 0.82 PTGS2 (0.61) PTGS2TNKS2ALOX5AKR1B1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120077345-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-29 US disclosed
US-7476476-B2 Photosensitive resin composition, electronic component using the same, and display unit using the same TORAY INDUSTRIES, INC. (JP) 2009-01-13 US disclosed