Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | SHBG | P04278 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930805 | 0.90 | TNKS2 (0.56) | TNKS2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL211114 | 0.90 | SHBG (0.58) | TNKS2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15698190 | 0.89 | TNKS2 (0.60) | KDM4ECASP6MAPTTNKS2PDE4A | |
| SCHEMBL10130847 | 0.89 | PTGS2 (0.52) | KDM4ECASP6MAPTTNKS2PDE4A | |
| SCHEMBL14606346 | 0.89 | SHBG (0.56) | KDM4EMAPTTNKS2PDE4APDE4B | |
| SCHEMBL10130966 | 0.89 | TRPV1 (0.52) | KDM4ECASP6MAPTTNKS2PDE4A | |
| SCHEMBL1067240 | 0.87 | TNKS2 (0.55) | KDM4EMAPTTNKS2PDE4APDE4B | |
| Guaiacol SCHEMBL11051755 | 0.87 | TSHR (0.55) | KDM4ECASP6MAPTTNKS2ALOX5 | |
| SCHEMBL15221748 | 0.85 | TNKS2 (0.51) | TNKS2PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10130851 | 0.85 | SHBG (0.56) | KDM4EMAPTTNKS2PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946482-B1 | METHOD FOR PREPARING A 4-HYDROXYBENZALDEHYDE AND DERIVATIVES | RHODIA CHIMIE SA (FR) | 2002-07-24 | — | — | EP | claimed |
| US-6184421-B1 | SELECTIVE OXIDATION, TO A CARBOXY GROUP, OF THE GROUP IN THE 2 POSITION WITH RESPECT TO THE HYDROXYL GROUPS OF A MIXTURE OF PHENOLS HAVING FORMYL AND/OR HYDROXYMETHYL GROUPS IN POSITIONS 2 OR 4; PREPARING VANILLIN AND ETHYL VANILLIN | RHODIA CHIMIE (FR) | 2001-02-06 | — | — | US | claimed |
| EP-0773919-B1 | METHOD FOR PREPARING 3-CARBOXY-4-HYDROXYBENZALDEHYDES AND DERIVATIVES THEREOF | RHODIA CHIMIE SA (FR) | 2000-09-20 | — | — | EP | claimed |
| EP-0946482-A1 | METHOD FOR PREPARING A 4-HYDROXYBENZALDEHYDE AND DERIVATIVES | RHODIA CHIMIE (FR) | 1999-10-06 | — | — | EP | claimed |
| US-5783737-A | Process for the preparation of 3-carboxy-4-hydroxybenzaldehides and derivatives thereof | RHONE-POULENC CHIMIE (FR) | 1998-07-21 | — | — | US | claimed |
| WO-1998022419-A1 | METHOD FOR PREPARING A 4-HYDROXYBENZALDEHYDE AND DERIVATIVES | RHODIA CHIMIE (FR) | 1998-05-28 | — | — | WO | claimed |
| EP-0773919-A1 | METHOD FOR PREPARING 3-CARBOXY-4-HYDROXYBENZALDEHYDES AND DERIVATIVES THEREOF | RHONE-POULENC CHIMIE (FR) | 1997-05-21 | — | — | EP | claimed |
| WO-1996037454-A1 | METHOD FOR PREPARING 3-CARBOXY-4-HYDROXYBENZALDEHYDES AND DERIVATIVES THEREOF | RHONE-POULENC CHIMIE (FR) | 1996-11-28 | — | — | WO | claimed |
| EP-0044260-B1 | PROCESS FOR THE PREPARATION OF POLYPHENOLS OPTIONALLY SUBSTITUTED BY AN ALDEHYDE GROUP | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-04-11 | — | — | EP | claimed |
| US-4435601-A | OXIDATION WITH HYDROGEN PEROXIDE IN ALKALI OR ALKALINE METAL BASE | RHONE-POULENC INDUSTRIES (FR) | 1984-03-06 | — | — | US | claimed |
| EP-2321247-B1 | METHOD FOR SEPARATING AROMATIC ALDEHYDE | RHODIA OPERATIONS (FR) | 2016-02-17 | — | — | EP | disclosed |
| US-20150344507-A1 | PHOSPHORUS-CONTAINING COMPOUNDS USEFUL FOR MAKING HALOGEN-FREE, IGNITION-RESISTANT POLYMERS | BLUE CUBE IP LLC (US) | 2015-12-03 | — | — | US | disclosed |
| US-20150126690-A1 | PHOSPHORUS-CONTAINING COMPOUNDS USEFUL FOR MAKING HALOGEN-FREE, IGNITION-RESISTANT POLYMERS | BLUE CUBE IP LLC | 2015-05-07 | — | — | US | disclosed |
| US-9018421-B2 | Separation of aromatic aldehydes | RHODIA OPERATIONS (FR) | 2015-04-28 | — | — | US | disclosed |
| US-8962773-B2 | Phosphorus-containing compounds useful for making halogen-free, ignition-resistant polymers | DOW GLOBAL TECHNOLOGIES LLC (US) | 2015-02-24 | — | — | US | disclosed |
| EP-0485613-A1 | PROCESS FOR PARA-METHYLOLATING PHENOLIC COMPOUND | MITSUBISHI CHEMICAL CORPORATION (JP) | 1992-05-20 | — | — | EP | disclosed |
| US-5019656-A | Hydroxymethylation of a Phenol, Basic Catalyst, Crown Compound | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-05-28 | — | — | US | disclosed |
| EP-0386639-A1 | Process for preparing para-hydroxybenzyl alcohol | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-09-12 | — | — | EP | disclosed |
| US-4435601-A | OXIDATION WITH HYDROGEN PEROXIDE IN ALKALI OR ALKALINE METAL BASE | RHONE-POULENC INDUSTRIES (FR) | 1984-03-06 | — | — | US | disclosed |
| US-4119671-A | OXIDATION OF HYDROXYBENZYL ALCOHOLS, PLATINUM CATALYST, ACTIVATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150344507-A1 | PHOSPHORUS-CONTAINING COMPOUNDS USEFUL FOR MAKING HALOGEN-FREE, IGNITION-RESISTANT POLYMERS | PFAS, EBNA1BP2, PIP5K1A | KDM4E 1179/4885CASP6 4062/4885MAPT 3337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.