Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 7/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.59 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TLR2 | O60603 | 6/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.49 |
| ▸ | PRKCG | P05129 | 1/20 | 0.49 |
| ▸ | PRKCB | P05771 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | PRKCH | P24723 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.49 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.49 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.49 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.49 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.49 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.47 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25869722 | 1.00 | LPAR1 (0.59) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL25869733 | 1.00 | LPAR1 (0.59) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL17447015 | 1.00 | LPAR1 (0.59) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL14818813 | 1.00 | LPAR1 (0.59) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL19075317 | 1.00 | LPAR1 (0.59) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL12648546 | 1.00 | LPAR1 (0.59) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL8406084 | 1.00 | LPAR1 (0.59) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL8406194 | 1.00 | LPAR1 (0.59) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL12990768 | 1.00 | LPAR1 (0.59) | LPAR1LPAR3LPAR2DNM1USP2 | |
| SCHEMBL18512649 | 0.98 | LPAR1 (0.57) | LPAR1LPAR3LPAR2DNM1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12023383-B2 | Lipid compositions | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-07-02 | — | — | US | disclosed |
| US-20240066129-A1 | LIPID COMPOSITIONS | ARBUTUS BIOPHARMA CORPORATION (US) | 2024-02-29 | — | — | US | disclosed |
| US-20130202652-A1 | METHODS AND COMPOSITIONS FOR DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| US-20130202652-A1 | METHODS AND COMPOSITIONS FOR DELIVERY OF ACTIVE AGENTS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2013-08-08 | — | — | US | disclosed |
| US-8158601-B2 | Lipid formulation | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-8158601-B2 | Lipid formulation | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-04-17 | — | — | US | disclosed |
| US-20100324120-A1 | LIPID FORMULATION | BANK OF AMERICA, N.A. | 2010-12-23 | — | — | US | disclosed |
| US-20100324120-A1 | LIPID FORMULATION | BANK OF AMERICA, N.A. | 2010-12-23 | — | — | US | disclosed |
| US-20090247608-A1 | Targeting Lipids | ALNYLAM PHARMACEUTICALS, INC. (US) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247608-A1 | Targeting Lipids | LY96, ABHD10, APOB | LPAR1 4/4885LPAR3 17/4885LPAR2 5/4885 |
| US-20100324120-A1 | LIPID FORMULATION | CETP, LIPA, SGMS1 | LPAR1 91/4885LPAR3 107/4885LPAR2 96/4885 |
| US-20240066129-A1 | LIPID COMPOSITIONS | SGMS1, SGMS2, LIPA | LPAR1 196/4885LPAR3 253/4885LPAR2 256/4885 |
| US-12023383-B2 | Lipid compositions | SGMS1, SGMS2, LIPA | LPAR1 196/4885LPAR3 253/4885LPAR2 256/4885 |
| US-20130202652-A1 | METHODS AND COMPOSITIONS FOR DELIVERY OF ACTIVE AGENTS | FUCA1, FUCA2, ANXA2 | LPAR1 178/4885LPAR3 133/4885LPAR2 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.