Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR8 | P51685 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24435818 | 0.85 | EPHX2 (0.50) | CCR8BRD4ALDH1A1EPHX2EPHX1 | |
| SCHEMBL2980571 | 0.85 | ALDH1A1 (0.38) | CCR8ALDH1A1NPY5REPHX2EPHX1 | |
| SCHEMBL2754308 | 0.84 | DPP4 (0.39) | CCR8JAK2BRD4ALDH1A1NPY5R | |
| SCHEMBL5540753 | 0.83 | ALDH1A1 (0.41) | ALDH1A1NPY5REPHX2EPHX1LMNA | |
| SCHEMBL10115727 | 0.81 | LMNA (0.47) | ALDH1A1EPHX2EPHX1KDM4EHSD17B10 | |
| SCHEMBL10115725 | 0.77 | LMNA (0.57) | ALDH1A1EPHX2EPHX1KDM4EHSD17B10 | |
| SCHEMBL12048931 | 0.75 | CA12 (0.50) | ALDH1A1NPY5RKDM4ELMNACA12 | |
| SCHEMBL17404846 | 0.75 | NPY5R (0.34) | NPY5RCA12CA1 | |
| SCHEMBL12882021 | 0.75 | LMNA (0.53) | CCR8ALDH1A1EPHX2KDM4ELMNA | |
| SCHEMBL2754307 | 0.74 | ALDH1A1 (0.36) | CCR8ALDH1A1EPHX2EPHX1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8115027-B2 | NPY Y5 antagonist | SHIONOGI & CO., LTD. (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20100292500-A1 | NPY Y5 ANTAGONIST | KAWANISHI YASUYUKI | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292500-A1 | NPY Y5 ANTAGONIST | NPY5R, NPY1R, NPY2R | CCR8 394/4885JAK2 1066/4885BRD4 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.