Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | CCR8 | P51685 | 2/20 | 0.34 |
| ▸ | SFRP1 | Q8N474 | 4/20 | 0.34 |
| ▸ | WNT3 | P56703 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24435818 | 0.86 | EPHX2 (0.50) | ALDH1A1EPHX2EPHX1CCR8MEN1 | |
| SCHEMBL10133512 | 0.85 | CCR8 (0.41) | ALDH1A1NPY5RLMNAEPHX2EPHX1 | |
| SCHEMBL5540753 | 0.85 | ALDH1A1 (0.41) | ALDH1A1NPY5RLMNAEPHX2EPHX1 | |
| SCHEMBL10115727 | 0.82 | LMNA (0.47) | ALDH1A1LMNAEPHX2EPHX1 | |
| SCHEMBL2754308 | 0.82 | DPP4 (0.39) | ALDH1A1NPY5RLMNAEPHX2EPHX1 | |
| SCHEMBL10115725 | 0.79 | LMNA (0.57) | ALDH1A1LMNAEPHX2EPHX1 | |
| SCHEMBL10115579 | 0.77 | ALDH1A1 (0.55) | ALDH1A1LMNACCR8 | |
| SCHEMBL12048931 | 0.77 | CA12 (0.50) | ALDH1A1NPY5RLMNAKMT2A | |
| SCHEMBL17404846 | 0.77 | NPY5R (0.34) | NPY5R | |
| SCHEMBL25219294 | 0.77 | CA1 (0.50) | EPHX2EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7781461-B2 | NPY Y5 antagonist | KAWANISHI YASUYUKI | 2010-08-24 | — | — | US | disclosed |
| US-20070015762-A1 | NPY Y5 antagonist | KAWANISHI YASUYUKI | 2007-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015762-A1 | NPY Y5 antagonist | NPY5R, NPY1R, NPY2R | ALDH1A1 4558/4885NPY5R 1/4885LMNA 1925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.