SCHEMBL10134043

SCHEMBL10134043

C=C1C(=O)N(CC)c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.55
HSD17B10 Q99714 1/20 0.55
KDM4E B2RXH2 2/20 0.54
MAPT P10636 2/20 0.54
TP53 P04637 1/20 0.54
HTT P42858 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.53
HPGD P15428 1/20 0.53
CASP1 P29466 1/20 0.53
MPI P34949 1/20 0.53
CACNA1B Q00975 1/20 0.53
APBA1 Q02410 1/20 0.53
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CES1 P23141 3/20 0.47
BCHE P06276 1/20 0.47
TGM2 P21980 1/20 0.47
ALDH2 P05091 1/20 0.46
ALDH3A1 P30838 1/20 0.46
CA12 O43570 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22473980 0.84 ALDH1A1 (0.65) ALDH1A1HSD17B10KDM4EMAPTTP53
SCHEMBL12659970 0.84 MEN1 (0.46) ALDH1A1HSD17B10KDM4EMAPTTP53
SCHEMBL5114051 0.81 CES1 (0.71) ALDH1A1HSD17B10CES1BCHETGM2
SCHEMBL29649695 0.81 CES1 (0.71) ALDH1A1HSD17B10CES1BCHETGM2
SCHEMBL12930176 0.79 ALDH1A1 (0.70) ALDH1A1HSD17B10MAPTTP53CES1
SCHEMBL15571795 0.78 ALDH1A1 (0.55) ALDH1A1HSD17B10KDM4EMAPTTP53
SCHEMBL22590720 0.75 MEN1 (0.46) ALDH1A1HSD17B10KDM4EMAPTTP53
SCHEMBL19543287 0.75 ALDH1A1 (0.54) ALDH1A1HSD17B10KDM4EMAPTTP53
SCHEMBL31107472 0.75 TTR (0.64) ALDH1A1KDM4EMAPTHTTHPGD
SCHEMBL6000324 0.75 TTR (0.64) ALDH1A1KDM4EMAPTHTTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9349965-B2 Photoelectric conversion material, film containing the material, photoelectric conversion device, method for preparing photoelectric conversion device, method for using photoelectric conversion device, photosensor and imaging device FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
US-9349965-B2 Photoelectric conversion material, film containing the material, photoelectric conversion device, method for preparing photoelectric conversion device, method for using photoelectric conversion device, photosensor and imaging device FUJIFILM CORPORATION (JP) 2016-05-24 US disclosed
WO-2015084731-A1 ALDEHYDE DEHYDROGENASE INHIBITORS AND METHODS OF USE THEREOF THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2015-06-11 WO disclosed
US-9035055-B2 Photoelectric conversion material, film containing the material, photoelectric conversion device, production method thereof, photosensor, imaging device and their use methods FUJIFILM CORPORATION (JP) 2015-05-19 US disclosed
US-9035055-B2 Photoelectric conversion material, film containing the material, photoelectric conversion device, production method thereof, photosensor, imaging device and their use methods FUJIFILM CORPORATION (JP) 2015-05-19 US disclosed
US-9012762-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-9012762-B2 Photoelectric conversion element and imaging device FUJIFILM CORPORATION (JP) 2015-04-21 US disclosed
US-20140374733-A1 PHOTOELECTRIC CONVERSION ELEMENT, METHOD FOR USING THE SAME, IMAGING DEVICE, PHOTOSENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
US-20140374733-A1 PHOTOELECTRIC CONVERSION ELEMENT, METHOD FOR USING THE SAME, IMAGING DEVICE, PHOTOSENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
EP-2786983-A1 Compounds for use in a photoelectric conversion material, and intermediates for the preparation thereof Fujifilm Corporation (JP) 2014-10-08 EP disclosed
US-20110056562-A1 PHOTOELECTRIC CONVERSION MATERIAL, FILM CONTAINING THE MATERIAL, PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR USE METHODS FUJIFILM CORPORATION (JP) 2011-03-10 US disclosed
US-20110056562-A1 PHOTOELECTRIC CONVERSION MATERIAL, FILM CONTAINING THE MATERIAL, PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR USE METHODS FUJIFILM CORPORATION (JP) 2011-03-10 US disclosed
US-20100308311-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308311-A1 PHOTOELECTRIC CONVERSION DEVICE AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308312-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308372-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
US-20100308372-A1 PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2010-12-09 US disclosed
EP-2259359-A2 Photoelectric conversion device, production method thereof and imaging device Fujifilm Corporation (JP) 2010-12-08 EP disclosed
US-20090223566-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-09-10 US disclosed
US-20090223566-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110056562-A1 PHOTOELECTRIC CONVERSION MATERIAL, FILM CONTAINING THE MATERIAL, PHOTOELECTRIC CONVERSION DEVICE, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR USE METHODS H1-0, CRY1, PYM1 ALDH1A1 1266/4885HSD17B10 3228/4885KDM4E 507/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.