SCHEMBL10134055

SCHEMBL10134055

C=C1CC(=S)N(CC)C1=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 1/20 0.37
ELANE P08246 1/20 0.37
CTSG P08311 1/20 0.37
CTRC Q99895 1/20 0.37
ALDH1A1 P00352 8/20 0.33
LMNA P02545 2/20 0.33
MAPT P10636 2/20 0.33
POLB P06746 2/20 0.33
MAPK1 P28482 2/20 0.33
GMNN O75496 1/20 0.33
THPO P40225 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MGLL Q99685 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL411262 0.78 F2 (0.40) F2ELANECTSGCTRCALDH1A1
SCHEMBL24186596 0.69 ALDH1A1 (0.33) F2ELANECTSGCTRCALDH1A1
SCHEMBL5838305 0.68 GMNN (0.32) F2ELANECTSGCTRCALDH1A1
SCHEMBL12194191 0.68 F2 (0.39) F2ELANECTSGCTRCALDH1A1
SCHEMBL24415370 0.67 F2 (0.35) F2ELANECTSGCTRCALDH1A1
SCHEMBL10134039 0.67 MEN1 (0.46) F2ELANECTSGCTRCALDH1A1
SCHEMBL4903716 0.67 CYP19A1 (0.33) F2ELANECTSGCTRCALDH1A1
SCHEMBL24220321 0.67 F2 (0.42) F2ELANECTSGCTRCALDH1A1
SCHEMBL409034 0.64 KDM4E (0.44) ALDH1A1MAPTPOLBBLMMGLL
SCHEMBL18346807 0.64 F2 (0.43) F2ELANECTSGCTRCALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD FUJIFILM CORPORATION (JP) 2012-04-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120080585-A1 PHOTOELECTRIC CONVERSION ELEMENT, PRODUCTION METHOD THEREOF, PHOTOSENSOR, IMAGING DEVICE AND THEIR DRIVING METHOD SUN2, CYBA, PPOX F2 2525/4885ELANE 3365/4885CTSG 4498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.