SCHEMBL4903716

SCHEMBL4903716

C=C1CC(=O)N(CCC)C1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 1/20 0.33
KDM4E B2RXH2 1/20 0.33
F2 P00734 1/20 0.32
ELANE P08246 1/20 0.32
CTSG P08311 1/20 0.32
CTRC Q99895 1/20 0.32
GAA P10253 3/20 0.32
MAPT P10636 3/20 0.32
KMT2A Q03164 2/20 0.32
HSD17B10 Q99714 2/20 0.32
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
HTT P42858 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ALDH1A1 P00352 3/20 0.31
PKM P14618 1/20 0.31
THRB P10828 1/20 0.31
APAF1 O14727 1/20 0.30
CASP1 P29466 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL409034 0.88 KDM4E (0.44) CYP19A1KDM4EGAAMAPTKMT2A
SCHEMBL6835923 0.87 MAPT (0.35) KDM4EGAAMAPTKMT2AHSD17B10
SCHEMBL11136205 0.86 MGLL (0.44) CYP19A1KDM4EGAAMAPTKMT2A
SCHEMBL18840672 0.85 MGLL (0.47) CYP19A1KDM4EGAAMAPTKMT2A
SCHEMBL5970022 0.85 MGLL (0.47) CYP19A1KDM4EGAAMAPTKMT2A
SCHEMBL410345 0.85 MGLL (0.47) CYP19A1KDM4EGAAMAPTKMT2A
SCHEMBL406778 0.85 MGLL (0.47) CYP19A1KDM4EGAAMAPTKMT2A
SCHEMBL411262 0.83 F2 (0.40) F2ELANECTSGCTRCMAPT
SCHEMBL13864166 0.81 MAPT (0.43) KDM4EGAAMAPTKMT2AMEN1
SCHEMBL4895048 0.79 MAPT (0.32) KDM4EGAAMAPTKMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220260909-A1 NEGATIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-08-18 US disclosed
US-8871861-B2 Silicone compound, photocurable liquid ink using the silicone compound, and method of manufacturing the ink RICOH COMPANY, LTD. (JP) 2014-10-28 US disclosed
EP-2711402-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSTIVE ADHESIVE SHEET Nitto Denko Corporation (JP) 2014-03-26 EP disclosed
US-20140066557-A1 PRESSURE-SENSITIVE ADHESIVE COMPOSITION AND PRESSURE-SENSITIVE ADHESIVE SHEET NITTO DENKO CORPORATION (JP) 2014-03-06 US disclosed
US-20080003288-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2008-01-03 US disclosed
US-7204997-B2 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2007-04-17 US disclosed
EP-1478403-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA, INC. (CA) 2004-11-24 EP disclosed
US-20030152623-A1 Responsive microgel and methods related thereto SUPRATEK PHARMA INC. (CA) 2003-08-14 US disclosed
WO-2003063909-A1 RESPONSIVE MICROGEL AND METHODS RELATED THERETO SUPRATEK PHARMA INC. (US) 2003-08-07 WO disclosed
US-6491903-B1 NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY WASHINGTON UNIVERSITY 2002-12-10 US disclosed
US-6383500-B1 Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications WASHINGTON UNIVERSITY 2002-05-07 US disclosed