SCHEMBL10136110

SCHEMBL10136110

O=C(CC1C(O)OC(CO)[C@@H](O[C@@H]2OC(CO)[C@H](O)[C@H](O)C2O)[C@@H]1O)OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LGALS8 O00214 1/20 0.51
HRAS P01112 1/20 0.48
SLC6A2 P23975 2/20 0.45
LGALS9 O00182 1/20 0.44
LGALS1 P09382 1/20 0.44
LGALS3 P17931 1/20 0.44
LGALS7; LGALS7B P47929 1/20 0.44
SYNJ2 O15056 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ABL1 P00519 1/20 0.44
ALPL P05186 1/20 0.44
POLB P06746 1/20 0.44
ALPI P09923 1/20 0.44
GAA P10253 1/20 0.44
MAPT P10636 1/20 0.44
ALPG P10696 1/20 0.44
PABPC1 P11940 1/20 0.44
RECQL P46063 1/20 0.44
GALK1 P51570 1/20 0.44
CASP7 P55210 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21391541 0.82 LGALS8 (0.49) LGALS8HRASSLC6A2LGALS9LGALS1
SCHEMBL21391509 0.81 LGALS8 (0.48) LGALS8HRASSLC6A2LGALS9LGALS1
SCHEMBL22906135 0.81 LGALS8 (0.48) LGALS8HRASSLC6A2LGALS9LGALS1
SCHEMBL21391539 0.81 LGALS8 (0.48) LGALS8HRASSLC6A2LGALS9LGALS1
SCHEMBL24478899 0.80 HRAS (0.55) LGALS8HRASSLC6A2LGALS9LGALS1
SCHEMBL8773137 0.79 SLC6A2 (0.58) LGALS8HRASSLC6A2LGALS9LGALS1
SCHEMBL8378459 0.78 SLC6A2 (0.62) LGALS8HRASSLC6A2SYNJ2KDM4E
SCHEMBL8517268 0.78 SLC6A2 (0.62) LGALS8HRASSLC6A2SYNJ2KDM4E
SCHEMBL5497498 0.78 SLC6A2 (0.58) LGALS8HRASSLC6A2LGALS9LGALS1
SCHEMBL5497489 0.78 SLC6A2 (0.58) LGALS8HRASSLC6A2LGALS9LGALS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8207328-B2 Lactosamine derivatives GLYCOM APS (DK) 2012-06-26 US disclosed
US-20090234111-A1 Novel Lactosamine Derivatives GLYCOM APS (DK) 2009-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090234111-A1 Novel Lactosamine Derivatives B3GNT2, FUT6, FUT5 LGALS8 127/4885HRAS 3666/4885SLC6A2 2860/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.