Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000418 | 0.85 | ALOX15 (0.58) | MMP2MMP9ALOX15TSHRCASP1 | |
| SCHEMBL4000411 | 0.85 | ALOX15 (0.58) | MMP2MMP9ALOX15TSHRCASP1 | |
| SCHEMBL10137884 | 0.82 | TP53 (0.46) | MMP2MMP9TP53POLBTDP1 | |
| SCHEMBL6014725 | 0.78 | CA1 (0.50) | MMP2MMP9ALOX15TSHRCASP1 | |
| SCHEMBL7582809 | 0.78 | CA2 (0.47) | TSHRTDP1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20356911 | 0.77 | CA1 (0.49) | MMP2MMP9ALOX15TSHRCASP1 | |
| SCHEMBL10137886 | 0.72 | NPC1 (0.41) | MMP2MMP9ALOX15TSHRCASP1 | |
| SCHEMBL12336359 | 0.71 | PTPN1 (0.46) | MMP2MMP9TP53RAB9ANPC1 | |
| SCHEMBL17321557 | 0.69 | POLB (0.56) | TSHRPOLBMEN1KMT2AKDM4E | |
| SCHEMBL9333789 | 0.69 | CA12 (0.46) | ALOX15TSHRCASP1NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389745-B2 | Phosphonate fluorescent dyes and conjugates | ELITECH HOLDING B.V. (NL) | 2013-03-05 | — | — | US | disclosed |
| US-20120116079-A1 | PHOSPHONATE FLUORESCENT DYES AND CONJUGATES | ELITECHGROUP MDX LLC | 2012-05-10 | — | — | US | disclosed |