Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4000411 | 1.00 | ALOX15 (0.58) | ALOX15TSHRCASP1RAB9ANPC1 | |
| SCHEMBL6014725 | 0.89 | CA1 (0.50) | ALOX15TSHRCASP1RAB9ANPC1 | |
| SCHEMBL20356911 | 0.87 | CA1 (0.49) | ALOX15TSHRCASP1RAB9ANPC1 | |
| SCHEMBL10137864 | 0.85 | MMP2 (0.43) | ALOX15TSHRCASP1RAB9ANPC1 | |
| SCHEMBL9333789 | 0.81 | CA12 (0.46) | ALOX15TSHRCASP1NPC1KDM4E | |
| SCHEMBL12336359 | 0.80 | PTPN1 (0.46) | RAB9ANPC1GAATP53LMNA | |
| SCHEMBL1179970 | 0.76 | HSD17B1 (0.72) | ALOX15TSHRCASP1RAB9ANPC1 | |
| SCHEMBL6014360 | 0.74 | CA1 (0.51) | ALOX15TSHRCASP1RAB9ANPC1 | |
| SCHEMBL4650170 | 0.74 | ALOX15 (0.41) | ALOX15TSHRCASP1RAB9ANPC1 | |
| SCHEMBL12231198 | 0.74 | CA1 (0.51) | ALOX15TSHRCASP1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10894037-B2 | Inhibitors of bacterial two component signal transduction system and uses thereof | ACADEMIA SINICA (TW) | 2021-01-19 | — | — | US | disclosed |
| US-20190192487-A1 | INHIBITORS OF BACTERIAL TWO COMPONENT SIGNAL TRANSDUCTION SYSTEM AND USES THEREOF | ACADEMIA SINICA (TW) | 2019-06-27 | — | — | US | disclosed |
| EP-1344055-A4 | MATERIALS FOR ENHANCING STAINING OF BIOPOLYMERS IN MATRICES | INVITROGEN CORP (US) | 2009-03-25 | — | — | EP | disclosed |
| US-7144738-B2 | Materials for enhancing staining of biopolymers in matrices | WHITNEY SCOTT | 2006-12-05 | — | — | US | disclosed |
| US-20050170517-A1 | Materials for enhancing staining of biopolymers in matrices | INVITROGEN CORPORATION (US) | 2005-08-04 | — | — | US | disclosed |
| US-6878551-B2 | For proteins/polypeptides within polyacrylamide matrix; mass spectrometry | INVITROGEN CORPORATION (US) | 2005-04-12 | — | — | US | disclosed |
| US-20040038418-A1 | Materials for enhancing staining of biopolymers in matrices | INVITROGEN CORPORATION | 2004-02-26 | — | — | US | disclosed |
| US-6635489-B2 | Sensitizing the matrix with heteroaromatic compounds, contacting with reduceable metal salts to stain and detecting | INVITROGEN CORPORATION | 2003-10-21 | — | — | US | disclosed |
| EP-1344055-A1 | MATERIALS FOR ENHANCING STAINING OF BIOPOLYMERS IN MATRICES | INVITROGEN CORPORATION (US) | 2003-09-17 | — | — | EP | disclosed |
| US-20020137222-A1 | Materials for enhancing staining of biopolymers in matrices | INVITROGEN CORPORATION | 2002-09-26 | — | — | US | disclosed |
| WO-2002042764-A1 | MATERIALS FOR ENHANCING STAINING OF BIOPOLYMERS IN MATRICES | INVITROGEN CORPORATION (US) | 2002-05-30 | — | — | WO | disclosed |
| EP-0175371-B1 | METHOD FOR SILVER STAINING PROTEINS AND NUCLEIC ACIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-14 | — | — | EP | disclosed |
| US-4710319-A | Autofluorogram composition | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-12-01 | — | — | US | disclosed |
| EP-0175371-A2 | Method for silver staining proteins and nucleic acids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-03-26 | — | — | EP | disclosed |
| US-4575452-A | Kit for silver staining proteins and nucleic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10894037-B2 | Inhibitors of bacterial two component signal transduction system and uses thereof | PGLS, BLVRB, COASY | ALOX15 2434/4885TSHR 1763/4885CASP1 3835/4885 |
| US-20190192487-A1 | INHIBITORS OF BACTERIAL TWO COMPONENT SIGNAL TRANSDUCTION SYSTEM AND USES THEREOF | PGLS, BLVRB, COASY | ALOX15 2434/4885TSHR 1763/4885CASP1 3835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.