Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 10/20 | 0.52 |
| ▸ | CPB1 | P15086 | 4/20 | 0.50 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14790038 | 0.85 | CPB2 (0.50) | CPB2CPB1KDM5AKDM5BGRIN2D | |
| SCHEMBL14551478 | 0.84 | CPB2 (0.39) | CPB2CPB1KDM4EALDH1A1USP2 | |
| SCHEMBL27803087 | 0.82 | CPB2 (0.53) | CPB2CPB1KDM5AKDM5BKDM4E | |
| SCHEMBL3012492 | 0.81 | CPB2 (0.52) | CPB2CPB1KDM5AKDM5BGRIN2D | |
| SCHEMBL13563916 | 0.80 | CYP2C9 (0.46) | KDM5BKDM4EALDH1A1USP2 | |
| SCHEMBL8865798 | 0.77 | CDK5 (0.54) | CPB2KDM5AKDM5BKDM4EALDH1A1 | |
| SCHEMBL31006001 | 0.77 | KDM4E (0.37) | CPB2CPB1KDM4EALDH1A1USP2 | |
| SCHEMBL8865591 | 0.76 | CDK5 (0.42) | KDM5AKDM5BALDH1A1USP2 | |
| SCHEMBL8348975 | 0.76 | CPB2 (0.57) | CPB2CPB1KDM5AKDM5BGRIN2D | |
| SCHEMBL18098599 | 0.76 | KDM4E (0.40) | KDM5BKDM4EALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040924-A1 | PURINE NUCLEOSIDE MONOPHOSPHATE PRODRUGS FOR TREATMENT OF CANCER AND VIRAL INFECTIONS | EMORY UNIVERSITY (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040924-A1 | PURINE NUCLEOSIDE MONOPHOSPHATE PRODRUGS FOR TREATMENT OF CANCER AND VIRAL INFECTIONS | PNP, HAVCR2, TYMP | CPB2 1610/4885CPB1 2213/4885KDM5A 2633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.