Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12801007 | 0.88 | KDM1A (0.41) | TUBB1ALDH1A1KDM4EL3MBTL1CYP1A2 | |
| SCHEMBL13140816 | 0.81 | TSHR (0.36) | TUBB1ALDH1A1KDM4EL3MBTL1CYP1A2 | |
| SCHEMBL2123778 | 0.80 | TUBB1 (0.40) | TUBB1ALDH1A1KDM4EL3MBTL1CYP1A2 | |
| SCHEMBL14190820 | 0.80 | ALDH1A1 (0.44) | TUBB1ALDH1A1KDM4EL3MBTL1CYP1A2 | |
| SCHEMBL10909552 | 0.78 | ALDH1A1 (0.48) | TUBB1ALDH1A1KDM4EL3MBTL1CYP1A2 | |
| SCHEMBL17527769 | 0.78 | L3MBTL1 (0.48) | TUBB1ALDH1A1KDM4EL3MBTL1CYP1A2 | |
| SCHEMBL9196941 | 0.78 | ALDH1A1 (0.48) | TUBB1ALDH1A1KDM4EL3MBTL1HSD17B10 | |
| SCHEMBL27634810 | 0.76 | ALDH1A1 (0.41) | TUBB1ALDH1A1KDM4EL3MBTL1CYP1A2 | |
| SCHEMBL12645303 | 0.74 | TSHR (0.41) | TUBB1ALDH1A1L3MBTL1HSD17B10TSHR | |
| SCHEMBL5042606 | 0.74 | LMNA (0.45) | TUBB1ALDH1A1KDM4EL3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2444393-A1 | Methods for producing cyclic benzamidine derivatives | Eisai R&D Management Co., Ltd. (JP) | 2012-04-25 | — | — | EP | disclosed |
| US-7375236-B2 | Methods for producing cyclic benzamidine derivatives | EISAI CO., LTD. (JP) | 2008-05-20 | — | — | US | disclosed |