Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | GFER | P55789 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | TLR4 | O00206 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 1/20 | 0.50 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | BCR | P11274 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | PRKACG | P22612 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24270240 | 0.79 | MEN1 (0.59) | MEN1KMT2AGFERKDM4EMAPT | |
| SCHEMBL3888498 | 0.79 | MEN1 (0.55) | MEN1KMT2AGFERKDM4EMAPT | |
| SCHEMBL29590223 | 0.79 | MEN1 (0.55) | MEN1KMT2AGFERKDM4EMAPT | |
| SCHEMBL6804201 | 0.79 | ABL1 (0.60) | MEN1KMT2AGFERKDM4EMAPT | |
| SCHEMBL23770974 | 0.79 | MEN1 (0.47) | MEN1KMT2AGFERMAPK10SMN1; SMN2 | |
| SCHEMBL1062981 | 0.79 | MEN1 (0.50) | MEN1KMT2AGFERKDM4EMAPT | |
| SCHEMBL8471004 | 0.79 | EGFR (0.53) | MEN1KMT2AGFERMAPK10TLR4 | |
| SCHEMBL4667858 | 0.79 | KDM4E (0.53) | MEN1KMT2AGFERKDM4EMAPT | |
| SCHEMBL6837492 | 0.79 | RAB9A (0.63) | MEN1KMT2AGFERKDM4EMAPT | |
| SCHEMBL3957102 | 0.79 | HTR3E (0.58) | MEN1KMT2AGFERMAPK10TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012059932-A1 | 2, 4 -DIAMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2012-05-10 | — | — | WO | disclosed |
| CN-101778832-A | Oxopyrazine derivative and weedicide | KUMIAI CHEMICAL INDUSTRY CO | 2010-07-14 | — | — | CN | disclosed |
| CN-1036650-C | process for the preparation of sulfonamide derivatives | EISAI CO LTD (JP) | 1997-12-10 | — | — | CN | disclosed |
| CN-1136036-A | Sulfonamide derivatives | EISAI CO LTD (JP) | 1996-11-20 | — | — | CN | disclosed |
| CN-1059519-A | Sulfonamide derivatives | EISAI CO LTD (JP) | 1992-03-18 | — | — | CN | disclosed |