Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.43 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7977426 | 0.92 | CNR1 (0.48) | CNR1CNR2FAAHMGLLNPBWR1 | |
| SCHEMBL7973344 | 0.88 | CYP19A1 (0.53) | CNR1CNR2PTGDR2GABRA2MAPT | |
| SCHEMBL10140554 | 0.81 | ALDH1A1 (0.43) | CNR1CNR2FAAHMGLLNPBWR1 | |
| SCHEMBL10140272 | 0.80 | MEN1 (0.48) | CNR1CNR2FAAHMGLLNPBWR1 | |
| SCHEMBL20307720 | 0.78 | CYP19A1 (0.63) | MAPTSMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8887875 | 0.77 | MEN1 (0.51) | NPBWR1PTGER4ERCC5FEN1AKR1C3 | |
| SCHEMBL10140278 | 0.77 | SMN1; SMN2 (0.48) | CNR1CNR2FAAHMGLLNPBWR1 | |
| SCHEMBL8888281 | 0.74 | AKR1C3 (0.48) | PTGER4ERCC5FEN1SLC16A3SLC16A1 | |
| SCHEMBL10140337 | 0.72 | CYP19A1 (0.51) | CNR1SMN1; SMN2NPC1POLBRAB9A | |
| SCHEMBL11254519 | 0.72 | PTGDR2 (0.60) | PTGDR2SMN1; SMN2MEN1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148363-B2 | Heterocyclic compounds as factor IXA inhibitors | SCHERING CORPORATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-20110065682-A1 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | MERCK SHARP & DOHME LLC | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110065682-A1 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | F9, F12, F8 | CNR1 2805/4885CNR2 3165/4885FAAH 583/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.