Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL888893 | 0.87 | CHRNA7 (0.36) | NAAACHRNA7EGLN1 | |
| SCHEMBL12413864 | 0.83 | CHRNA7 (0.34) | CHRNA7 | |
| SCHEMBL31698306 | 0.83 | CHRNA7 (0.34) | CHRNA7 | |
| SCHEMBL890116 | 0.82 | NPC1 (0.39) | METAP2EGLN1 | |
| SCHEMBL5018725 | 0.82 | NPC1 (0.45) | CHRNA7 | |
| SCHEMBL889387 | 0.82 | EGLN1 (0.44) | EGLN1 | |
| SCHEMBL2609367 | 0.80 | LTA4H (0.43) | EGLN1 | |
| SCHEMBL22184930 | 0.80 | GPR55 (0.40) | — | |
| SCHEMBL26971204 | 0.80 | MAPT (0.44) | — | |
| SCHEMBL10313050 | 0.78 | HPGDS (0.43) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021704-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |
| WO-2011091417-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-07-28 | — | — | WO | disclosed |
| WO-2011031934-A1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2011-03-17 | — | — | WO | disclosed |