Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 4/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | SIK1 | P57059 | 1/20 | 0.34 |
| ▸ | RIPK4 | P57078 | 1/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | DSTYK | Q6XUX3 | 1/20 | 0.34 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.34 |
| ▸ | NEK7 | Q8TDX7 | 3/20 | 0.33 |
| ▸ | RET | P07949 | 4/20 | 0.32 |
| ▸ | EIF2AK3 | Q9NZJ5 | 6/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369095 | 0.87 | GPR119 (0.32) | ADKRIPK2PDGFRBKITSRC | |
| SCHEMBL357038 | 0.83 | RIPK2 (0.38) | ADKRIPK2PDGFRBKITSRC | |
| SCHEMBL10140747 | 0.81 | MALT1 (0.37) | RIPK2PDGFRBKITSRCFLT3 | |
| SCHEMBL354783 | 0.80 | RIPK2 (0.35) | RIPK2PDGFRBKITSRCFLT3 | |
| SCHEMBL358364 | 0.80 | GPR119 (0.36) | ADKRIPK2PDGFRBKITSRC | |
| SCHEMBL355771 | 0.79 | GPR119 (0.49) | — | |
| SCHEMBL369097 | 0.79 | GPR119 (0.40) | ADKRIPK2PDGFRBKITSRC | |
| SCHEMBL356834 | 0.78 | RIPK2 (0.32) | RIPK2PDGFRBKITSRCFLT3 | |
| SCHEMBL356951 | 0.78 | RIPK2 (0.32) | ADKRIPK2PDGFRBKITSRC | |
| SCHEMBL354786 | 0.78 | GPR119 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016119-A1 | NOVEL PYRROLO(2,3-d)PYRIMIDINE COMPOUND | GPR119, GPR139, HCAR1 | ADK 2341/4885RIPK2 2742/4885PDGFRB 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.