SCHEMBL10141003

SCHEMBL10141003

CC(C)CCN[C@H](C)CCCCO

nearest known ligand 0.38

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32
ADRB2 P07550 4/20 0.30
SLC29A1 Q99808 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5052380 0.86 SLC6A4 (0.38) LMNAADRB2
SCHEMBL5052257 0.86 SMN1; SMN2 (0.32) LMNAADRB2
Octamylamine SCHEMBL25207 0.81 LMNA (0.43) LMNAADRB2
SCHEMBL5052433 0.79 SMN1; SMN2 (0.33) LMNAADRB2
SCHEMBL1619443 0.79 SMN1; SMN2 (0.48) LMNAADRB2
SCHEMBL24305793 0.78 ADH1B (0.48) LMNAADRB2
SCHEMBL19917415 0.78 ADH1B (0.48) LMNAADRB2
SCHEMBL20996678 0.78 ALDH1A1 (0.33) ADRB2
SCHEMBL1619512 0.78 LMNA (0.50) LMNAADRB2
SCHEMBL1618292 0.77 SMN1; SMN2 (0.44) LMNAADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012055031-A1 HIV PROTEASE INHIBITORS MERCK CANADA INC. (CA) 2012-05-03 WO disclosed