Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL623009 | 0.84 | AGTR1 (0.62) | GLATDP1HTTKMT2AALDH1A1 | |
| SCHEMBL184604 | 0.83 | AGTR1 (0.64) | GLATDP1HTTKMT2AALDH1A1 | |
| SCHEMBL11148867 | 0.78 | TDP1 (0.66) | GLATDP1HTTKMT2AALDH1A1 | |
| SCHEMBL2517123 | 0.77 | MEN1 (0.62) | TDP1KMT2AALDH1A1USP2MEN1 | |
| SCHEMBL2517602 | 0.76 | ALDH1A1 (0.67) | TDP1ALDH1A1MAPTAGTR1KDM4E | |
| SCHEMBL1422197 | 0.76 | USP2 (0.65) | GLATDP1HTTKMT2AALDH1A1 | |
| SCHEMBL3000302 | 0.76 | USP2 (0.59) | TDP1KMT2AALDH1A1USP2MEN1 | |
| SCHEMBL12646347 | 0.75 | USP2 (0.68) | TDP1HTTKMT2AALDH1A1USP2 | |
| SCHEMBL3568101 | 0.75 | USP2 (0.68) | TDP1KMT2AALDH1A1USP2MEN1 | |
| SCHEMBL5453322 | 0.74 | MEN1 (0.58) | TDP1HTTKMT2AALDH1A1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020357-A1 | ACETAMIDE COMPOUNDS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS LTD. (IN) | 2012-02-16 | — | — | WO | disclosed |