SCHEMBL1014139

SCHEMBL1014139

COc1nc(C)nc(NC(=O)NS(=O)(=O)Nc2ccccc2C(C)=O)n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.40
RAB9A P51151 1/20 0.39
MAPK1 P28482 2/20 0.38
LMNA P02545 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HTT P42858 2/20 0.38
MEN1 O00255 2/20 0.36
ALDH1A1 P00352 2/20 0.36
KMT2A Q03164 2/20 0.36
ELANE P08246 1/20 0.36
PRTN3 P24158 1/20 0.36
PTK2 Q05397 1/20 0.36
POLB P06746 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10946143 0.91 TSHR (0.46) MAPK1LMNAHTTALDH1A1KMT2A
SCHEMBL1017166 0.89 ALOX15 (0.40) ALOX15LMNASMN1; SMN2HTTALDH1A1
SCHEMBL10944696 0.88 ALOX15 (0.42) ALOX15RAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL10945094 0.87 MAPT (0.46) ALOX15RAB9AMAPK1LMNASMN1; SMN2
SCHEMBL10641612 0.86 KDM4E (0.45) RAB9ALMNASMN1; SMN2HTTMEN1
SCHEMBL10948376 0.86 NPC1 (0.43) ALOX15LMNAMEN1ALDH1A1KMT2A
SCHEMBL9663368 0.85 GAA (0.43) ALOX15RAB9AHTTALDH1A1
SCHEMBL8380205 0.84 GAA (0.51) ALOX15RAB9AMAPK1SMN1; SMN2HTT
SCHEMBL11002649 0.83 NPC1 (0.45) ALDH1A1KDM4ETHRB
SCHEMBL1013413 0.83 TSHR (0.48) ALOX15LMNASMN1; SMN2HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0264467-B1 SULFAMOYL UREA DERIVATES PPG INDUSTRIES, INC. (US) 1992-06-24 EP claimed
US-4622065-A HERBICIDES PPG INDUSTRIES, INC. (US) 1986-11-11 US claimed
EP-0965265-B1 AHAS-inhibiting herbicide resistant wheat and method for selection thereof BASF SE (DE) 2011-01-05 EP disclosed
US-7034208-B1 Ahas inhibiting herbicide resistant wheat and method for selection thereof BASF AKTIENGELLSCHAFT (DE) 2006-04-25 US disclosed
US-6339184-B1 SCREENING FOR THE SELECTION OF MUTATIONS WHICH CONFER ACETOHYDROXYACID SYNTHASE RESISTANCE TO WHEAT BASF AKTIENGELLSCHAFT (DE) 2002-01-15 US disclosed
EP-0508161-B1 Use of AHAS inhibiting herbicide resistant wheat and method for selection thereof AMERICAN CYANAMID CO (US) 2000-05-10 EP disclosed
EP-0965265-A2 AHAS-inhibiting herbicide resistant wheat and method for selection thereof AMERICAN CYANAMID COMPANY (US) 1999-12-22 EP disclosed
WO-1995029902-A1 SUBSTITUTED PHENYL AMINOSULPHONYL UREAS BAYER AKTIENGESELLSCHAFT (DE) 1995-11-09 WO disclosed
EP-0508161-A1 AHAS inhibiting herbicide resistant wheat and method for selection thereof AMERICAN CYANAMID COMPANY (US) 1992-10-14 EP disclosed
EP-0264467-B1 SULFAMOYL UREA DERIVATES PPG INDUSTRIES, INC. (US) 1992-06-24 EP disclosed
EP-0264467-A1 Sulfamoyl urea derivates PPG INDUSTRIES, INC. (US) 1988-04-27 EP disclosed
US-4696695-A HERBICIDES PPG INDUSTRIES, INC. (US) 1987-09-29 US disclosed
US-4622065-A HERBICIDES PPG INDUSTRIES, INC. (US) 1986-11-11 US disclosed