SCHEMBL1017166

SCHEMBL1017166

CCC(=O)c1ccccc1NS(=O)(=O)NC(=O)Nc1nc(C)nc(OC)n1

nearest known ligand 0.55

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.40
ELANE P08246 1/20 0.39
PRTN3 P24158 1/20 0.39
TP53 P04637 3/20 0.39
MAPT P10636 1/20 0.38
ALDH1A1 P00352 3/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 2/20 0.37
NPC1 O15118 1/20 0.37
TSHR P16473 2/20 0.36
HSD17B10 Q99714 1/20 0.36
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10946143 0.89 TSHR (0.46) MAPTALDH1A1LMNAHTTKDM4E
SCHEMBL1014139 0.89 ALOX15 (0.40) ALOX15ELANEPRTN3ALDH1A1SMN1; SMN2
SCHEMBL1012916 0.85 GAA (0.48) ALOX15ELANEPRTN3TP53MAPT
SCHEMBL10944696 0.85 ALOX15 (0.42) ALOX15TP53MAPTSMN1; SMN2NPC1
SCHEMBL9248108 0.84 TSHR (0.48) ALOX15ELANEPRTN3TP53MAPT
SCHEMBL10945094 0.84 MAPT (0.46) ALOX15MAPTSMN1; SMN2LMNAHTT
SCHEMBL10948376 0.83 NPC1 (0.43) ALOX15TP53MAPTALDH1A1LMNA
SCHEMBL10611744 0.82 ALOX15 (0.41) ALOX15TP53MAPTALDH1A1KDM4E
SCHEMBL10945261 0.81 ALDH1A1 (0.42) ALOX15TP53MAPTALDH1A1SMN1; SMN2
SCHEMBL8536335 0.80 ALOX15 (0.39) ALOX15TP53ALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0965265-B1 AHAS-inhibiting herbicide resistant wheat and method for selection thereof BASF SE (DE) 2011-01-05 EP disclosed
US-7034208-B1 Ahas inhibiting herbicide resistant wheat and method for selection thereof BASF AKTIENGELLSCHAFT (DE) 2006-04-25 US disclosed
US-6339184-B1 SCREENING FOR THE SELECTION OF MUTATIONS WHICH CONFER ACETOHYDROXYACID SYNTHASE RESISTANCE TO WHEAT BASF AKTIENGELLSCHAFT (DE) 2002-01-15 US disclosed
EP-0508161-B1 Use of AHAS inhibiting herbicide resistant wheat and method for selection thereof AMERICAN CYANAMID CO (US) 2000-05-10 EP disclosed
EP-0965265-A2 AHAS-inhibiting herbicide resistant wheat and method for selection thereof AMERICAN CYANAMID COMPANY (US) 1999-12-22 EP disclosed
EP-0508161-A1 AHAS inhibiting herbicide resistant wheat and method for selection thereof AMERICAN CYANAMID COMPANY (US) 1992-10-14 EP disclosed