SCHEMBL1014151

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1016620	0.93	HDAC1 (0.39)	HDAC1HDAC6HDAC5HDAC8S1PR1
	SCHEMBL3737030	0.79	HDAC1 (0.53)	HDAC1HDAC6HDAC5HDAC8S1PR1
	SCHEMBL1012400	0.78	RAB9A (0.44)	S1PR1POLBEPHX2ALDH1A1RAB9A
	SCHEMBL3734645	0.76	HDAC1 (0.58)	HDAC1HDAC6HDAC5HDAC8S1PR1
	SCHEMBL3740043	0.76	HDAC1 (0.50)	HDAC1HDAC6HDAC5HDAC8S1PR1
	SCHEMBL3749726	0.76	NR1H4 (0.50)	HDAC1HDAC6HDAC5HDAC8S1PR1
	SCHEMBL1014887	0.73	RAB9A (0.46)	S1PR1S1PR3POLBALDH1A1NPSR1
	SCHEMBL1015208	0.73	RAB9A (0.44)	S1PR1S1PR3POLBALDH1A1RAB9A
	SCHEMBL1014093	0.72	S1PR1 (0.53)	S1PR1S1PR3ALDH1A1NPSR1RAB9A
	SCHEMBL11983603	0.71	S1PR1 (0.70)	S1PR1S1PR3ALDH1A1NPSR1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.