SCHEMBL1014887

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1012400	0.89	RAB9A (0.44)	RAB9ANPC1MAPTSMN1; SMN2TP53
	SCHEMBL4321698	0.86	S1PR1 (0.46)	RAB9ANPC1MAPTSMN1; SMN2TP53
	SCHEMBL1015208	0.82	RAB9A (0.44)	RAB9ANPC1MAPTSMN1; SMN2TP53
	SCHEMBL1014383	0.81	RAB9A (0.46)	RAB9ANPC1MAPTSMN1; SMN2TP53
	SCHEMBL1016620	0.78	HDAC1 (0.39)	RAB9ANPC1MAPTSMN1; SMN2TP53
	SCHEMBL12881066	0.73	L3MBTL1 (0.46)	RAB9ANPC1MAPTSMN1; SMN2TP53
	SCHEMBL1014151	0.73	HDAC1 (0.43)	RAB9ANPC1MAPTSMN1; SMN2TP53
	SCHEMBL1015459	0.72	S1PR1 (0.60)	S1PR1S1PR3
	SCHEMBL11983603	0.72	S1PR1 (0.70)	RAB9ANPC1MAPTSMN1; SMN2HPGD
	SCHEMBL1014369	0.72	NPC1 (0.55)	RAB9ANPC1MAPTSMN1; SMN2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.