Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 14/20 | 0.67 |
| ▸ | GALR1 | P47211 | 3/20 | 0.62 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143394 | 1.00 | GALR2 (0.67) | GALR2GALR1SLC2A1MAPTKMT2A | |
| SCHEMBL10143736 | 0.87 | GALR2 (0.53) | GALR2GALR1SLC2A1MAPTKMT2A | |
| SCHEMBL10143753 | 0.87 | KDM4E (0.55) | GALR2GALR1SLC2A1MAPTKMT2A | |
| SCHEMBL10143570 | 0.87 | GALR2 (0.53) | GALR2GALR1SLC2A1MAPTKMT2A | |
| SCHEMBL10143742 | 0.86 | JAK2 (0.53) | GALR2GALR1SLC2A1MAPTKMT2A | |
| SCHEMBL10144220 | 0.85 | GALR2 (0.66) | GALR2GALR1SLC2A1MAPTKMT2A | |
| SCHEMBL10144335 | 0.82 | GALR2 (0.71) | GALR2GALR1MAPTHTTTDP1 | |
| SCHEMBL10143440 | 0.82 | KMT2A (0.54) | GALR2MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL10143556 | 0.82 | GALR2 (0.80) | GALR2GALR1 | |
| SCHEMBL10143553 | 0.82 | GALR2 (0.48) | GALR2GALR1SLC2A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |