Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | PKLR | P30613 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GALR2 | O43603 | 3/20 | 0.51 |
| ▸ | AURKA | O14965 | 2/20 | 0.51 |
| ▸ | IKBKB | O14920 | 1/20 | 0.50 |
| ▸ | CHUK | O15111 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18161288 | 0.86 | KMT2A (0.60) | KMT2APKMNPC1PKLRRAB9A | |
| SCHEMBL10143454 | 0.85 | KMT2A (0.60) | KMT2APKMNPC1PKLRRAB9A | |
| SCHEMBL10143551 | 0.82 | GALR2 (0.67) | KMT2ASMN1; SMN2LMNAGALR2ALDH1A1 | |
| SCHEMBL10143394 | 0.82 | GALR2 (0.67) | KMT2ASMN1; SMN2LMNAGALR2ALDH1A1 | |
| SCHEMBL10143452 | 0.81 | KMT2A (0.56) | KMT2APKMNPC1PKLRRAB9A | |
| SCHEMBL10143742 | 0.81 | JAK2 (0.53) | KMT2ASMN1; SMN2GALR2AURKAMAPT | |
| SCHEMBL10143441 | 0.80 | GALR2 (0.74) | GALR2AURKA | |
| SCHEMBL10143570 | 0.79 | GALR2 (0.53) | KMT2ASMN1; SMN2GALR2AURKAALDH1A1 | |
| SCHEMBL18162473 | 0.78 | KMT2A (0.55) | KMT2APKMNPC1PKLRRAB9A | |
| SCHEMBL18153330 | 0.78 | KMT2A (0.61) | KMT2APKMNPC1PKLRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |