Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 11/20 | 0.53 |
| ▸ | GALR1 | P47211 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143551 | 0.87 | GALR2 (0.67) | GALR2GALR1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL10143394 | 0.87 | GALR2 (0.67) | GALR2GALR1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL10144220 | 0.87 | GALR2 (0.66) | GALR2GALR1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL10143457 | 0.83 | MAPT (0.61) | GALR2GALR1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL10143742 | 0.83 | JAK2 (0.53) | GALR2GALR1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL10143553 | 0.81 | GALR2 (0.48) | GALR2GALR1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL10143440 | 0.79 | KMT2A (0.54) | GALR2MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10144222 | 0.78 | GALR1 (0.81) | GALR2GALR1AURKA | |
| SCHEMBL10143455 | 0.78 | GALR2 (0.80) | GALR2GALR1MAPTTP53AURKA | |
| SCHEMBL27440444 | 0.77 | LMNA (0.44) | MAPTSMN1; SMN2MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |