Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ACP1 | P24666 | 3/20 | 0.48 |
| ▸ | GALR2 | O43603 | 5/20 | 0.47 |
| ▸ | GALR1 | P47211 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143570 | 0.83 | GALR2 (0.53) | MAPTSMN1; SMN2MEN1KMT2AGALR2 | |
| SCHEMBL10144223 | 0.81 | GALR2 (0.74) | MAPTGALR2GALR1 | |
| SCHEMBL10144221 | 0.81 | GALR2 (0.70) | MAPTSMN1; SMN2MEN1KMT2AACP1 | |
| SCHEMBL10143551 | 0.80 | GALR2 (0.67) | MAPTSMN1; SMN2MEN1KMT2AGALR2 | |
| SCHEMBL10143394 | 0.80 | GALR2 (0.67) | MAPTSMN1; SMN2MEN1KMT2AGALR2 | |
| SCHEMBL6016821 | 0.78 | MEN1 (0.71) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL10143742 | 0.76 | JAK2 (0.53) | MAPTSMN1; SMN2MEN1KMT2AGALR2 | |
| SCHEMBL10144220 | 0.76 | GALR2 (0.66) | MAPTSMN1; SMN2MEN1KMT2AGALR2 | |
| SCHEMBL10143440 | 0.75 | KMT2A (0.54) | MAPTSMN1; SMN2MEN1KMT2AGALR2 | |
| SCHEMBL10143553 | 0.72 | GALR2 (0.48) | MAPTSMN1; SMN2MEN1KMT2AGALR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |