Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.74 |
| ▸ | HTT | P42858 | 2/20 | 0.74 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CCR2 | P41597 | 4/20 | 0.50 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.50 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23997374 | 0.85 | LMNA (0.65) | LMNAHTTOPRM1CYP1A2KMT2A | |
| SCHEMBL30336777 | 0.85 | LMNA (0.65) | LMNAHTTOPRM1CYP1A2KMT2A | |
| Ethyl Propionate SCHEMBL11272931 | 0.85 | LMNA (0.58) | LMNAHTTOPRM1CYP1A2KMT2A | |
| SCHEMBL4917013 | 0.85 | LMNA (1.00) | LMNAHTTOPRM1CYP1A2KMT2A | |
| SCHEMBL2762074 | 0.85 | LMNA (0.81) | LMNAHTTOPRM1CYP1A2KMT2A | |
| SCHEMBL4920376 | 0.84 | LMNA (0.76) | LMNAHTTOPRM1CYP1A2KMT2A | |
| SCHEMBL10487828 | 0.83 | HPGD (0.74) | LMNAHTTOPRM1CYP1A2KMT2A | |
| SCHEMBL5244095 | 0.81 | EPHX2 (0.52) | LMNAHTTOPRM1CYP1A2EPHX2 | |
| SCHEMBL10487884 | 0.81 | ALDH1A1 (0.55) | LMNAHTTOPRM1CYP1A2KMT2A | |
| SCHEMBL23997482 | 0.81 | LMNA (0.75) | LMNAHTTOPRM1CYP1A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |