Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GALR2 | O43603 | 12/20 | 0.53 |
| ▸ | GALR1 | P47211 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10143551 | 0.87 | GALR2 (0.67) | GALR2GALR1MAPTPOLBSLC2A1 | |
| SCHEMBL10143394 | 0.87 | GALR2 (0.67) | GALR2GALR1MAPTPOLBSLC2A1 | |
| SCHEMBL10143753 | 0.84 | KDM4E (0.55) | GALR2GALR1MAPTKDM4ESLC2A1 | |
| SCHEMBL10143594 | 0.78 | GALR2 (0.80) | GALR2GALR1MAPTPOLB | |
| SCHEMBL10143615 | 0.77 | GALR2 (0.84) | GALR2GALR1 | |
| SCHEMBL13927340 | 0.77 | GALR2 (0.52) | GALR2GALR1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL13927343 | 0.75 | GALR2 (0.50) | GALR2GALR1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10144335 | 0.75 | GALR2 (0.71) | GALR2GALR1MAPTMAPK1TDP1 | |
| SCHEMBL10143570 | 0.74 | GALR2 (0.53) | GALR2GALR1MAPTSLC2A1SMN1; SMN2 | |
| SCHEMBL10143742 | 0.74 | JAK2 (0.53) | GALR2GALR1MAPTSLC2A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012009258-A2 | PEPTIDOMIMETIC GALANIN RECEPTOR MODULATORS | ROBERTS EDWARD (US) | 2012-01-19 | — | — | WO | disclosed |